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Grants to USA, Canada, and Israel Investigators for Research
into the Biological Causes of Anorexia Nervosa

Eating Disorders Research Grants Program

Agency Type:

Foundation / Corporation

Funding Source:

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The Klarman Family Foundation

Deadline Date:

12/09/19 1:00 PM EST

Description:

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Grants to USA, Canada, and Israel academic researchers for research related to anorexia nervosa. Funding is intended to support research by institution faculty members that has the potential to reveal the underlying biological factors of the disease, including the connection between behavior, cognition, and neurobiology.

Applicants may request funding for pilot studies or for research projects.

The fundamental aim of this grant program is to understand the biology underlying the psychiatric disease anorexia nervosa, with the goal of accelerating progress toward prevention and treatment.  The Klarman Foundation funds projects to research the biology of this disease and the questions of how and why it develops and persists. 

The Foundation seeks to fund well-controlled, sufficiently powered studies asking important questions about the interface between behavior/cognition and neurobiology. Approaches that incorporate neurobiology with an up-to-date understanding of the symptoms and dysfunction associated with anorexia nervosa are encouraged.

Moving from Genes to Mechanism:

Research to strengthen the connections between the epidemiology, genetic epidemiology, and molecular biology of this disease, and to identify the mechanisms through which genetic, environmental, and lifestyle factors lead to disease are encouraged. An anorexia nervosa genome-wide association study was published in Nature Genetics in July of 2019, involving approximately 17,000 AN cases in total and including nearly 13,000 cases from the Anorexia Nervosa Genetics Initiative (ANGI), an initiative of The Klarman Family Foundation. The Foundation encourages applications to build on these GWAS results.

Proposals may be submitted for human studies or for animal model studies:

Collaborative Projects: https://klarmanfoundation.org/wp-content/uploads/2020.ED_.RFA_.pdf#page=2

Resource Sharing: https://klarmanfoundation.org/wp-content/uploads/2020.ED_.RFA_.pdf#page=2

The Foundation is enthusiastic about attracting researchers with a strong track record in another field who can bring a new approach to eating disorders research. Bringing in investigators from other fields, such as those studying the neuro-circuitry of complex, motivated behavior (e.g. fear conditioning, reward behavior, and addiction research), remains a priority. 

GrantWatch ID#:

GrantWatch ID#: 131754

Estimated Size of Grant:

- 1-year pilot studies of up to $150,000 USD, inclusive of up to 10% indirect costs
- 1-3 year research projects of up to $250,000 USD per year, inclusive of up to 10% indirect costs

Term of Contract:

The Foundation funds grants to academic researchers for 1 – 3 year projects.

Funding Start Dates: July 1-October 1, 2020.

Additional Eligibility Criteria:

The Foundation funds grants to academic researchers. Applicants must hold a faculty appointment at a nonprofit, non-governmental academic, medical or research institution in the United States, Canada, or Israel.

A visiting or adjunct faculty position is acceptable at an institution in the above countries as long as this appointment is in place at the time of application and will be retained throughout the grant period. The letter from the department or division chair must confirm the duration of the appointment.

While this program is not specifically aimed at early-career faculty, applicant track record will be evaluated according to career stage and experience. Researchers who are new to the field are encouraged to consult with clinical experts in order to ensure a deep understanding of the behaviors associated with this disease before designing a research study.

Previous recipients of a Klarsman Family Foundation grant may not renew their current grants, but may may submit an application which will be competitively reviewed with all other submissions. Any outstanding reporting requirements for previous grants must be complete prior to submission of a new application.

Research into obesity, normal feeding behavior and/or negative energy balance, sickness-induced anorexia, PANS/PANDAS, other types of anorexia distinct from the psychiatric disease anorexia nervosa, behavioral therapy, the medical complications of eating disorders, and clinical trials are currently outside the scope of this program.

Pre-Application Information:

Application Deadline: December 9, 2019 (1:00 pm, U.S. Eastern Time).
Decisions by: May 2020.

There are no institutional limitations on the number of applications.

Only one application may be submitted by a PI and, therefore, s/he must decide whether to submit a pilot study or a multi-year grant. Proposals with multi-PIs must be pre-approved by KFF staff.

Download the application forms and budget template, complete, and save these and other requested documents as one PDF file. Submit online through the Foundation’s online portal.

Recording of a webinar for basic researchers who want a better understanding of the clinical aspects of Anorexia Nervosa: https://register.gotowebinar.com/recording/3018182904479175171

Summary results of a KFF-funded Delphi Panel study to define longitudinal stages of illness in Anorexia Nervosa: https://klarmanfoundation.org/wp-content/uploads/StagesIllnessPoster_190823.pdf

Contact Information:

Before starting your grant application, please review the funding source's website listed below for updates/changes/addendums/conferences/LOIs.

Click here to to access the online proposal form: https://klarman-portal.givingdata.com/campaign/EDResearch

Director of Medical and Scientific Research: edresearch@klarmanfoundation.org

Klarman Family Foundation
95 Berkeley Street, #208
Boston, MA 02116

URL for Full Text (RFP):

Geographic Focus:

USA: Alabama;   Alaska;   Arizona;   Arkansas;   California;   Colorado;   Connecticut;   Delaware;   Florida;   Georgia;   Hawaii;   Idaho;   Illinois;   Indiana;   Iowa;   Kansas;   Kentucky;   Louisiana;   Maine;   Maryland;   Massachusetts;   Michigan;   Minnesota;   Mississippi;   Missouri;   Montana;   Nebraska;   Nevada;   New Hampshire;   New Jersey;   New Mexico;   New York City;   New York;   North Carolina;   North Dakota;   Ohio;   Oklahoma;   Oregon;   Pennsylvania;   Rhode Island;   South Carolina;   South Dakota;   Tennessee;   Texas;   Utah;   Vermont;   Virginia;   Washington, DC;   Washington;   West Virginia;   Wisconsin;   Wyoming

Canada: Alberta;   British Columbia;   Manitoba;   New Brunswick;   Newfoundland and Labrador;   Northwest Territories;   Nova Scotia;   Nunavut;   Ontario;   Prince Edward Island;   Quebec;   Saskatchewan;   Yukon;

Israel

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