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BIRAX (the Britain Israel Research and Academic Exchange Partnership) Ageing Programme

Grants to UK and Israel Medical Scientists
for Collaborative Research Projects

Agency Type:

Foundation / Corporation

Funding Source:

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British Council and British Embassy in Israel

Conf. Date:

09/04/18

Deadline Date:

10/15/18 22:00 GMT

Description:

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Grants to UK and Israel research investigators employed in academic, research and hospital institutions for collaborative research in the field of aging. Funding is intended to develop scientific collaboration between researchers in the two countries and for innovative research in the area of aging.

The aim of BIRAX Ageing is twofold: (1) to advance innovative scientific research into aging and its impact on human health and to encourage the use of cutting edge technology, big data and personalized medicine in aging research (2) to develop meaningful, sustainable and mutually enriching scientific collaboration between researchers, labs and institutions in the UK and Israel that will further aging research for the benefit of humanity as a whole.

Funding Criteria:
- The primary consideration in ranking the proposals will be scientific excellence, novelty, focus on understanding disease mechanisms and use of advanced research strategies;
- Clear and direct relevance to the aging process and age-related disease;
- Proposals for interventions in the aging process in order to prevent or mitigate age-related disease;
- Proposals for diagnostic approaches (e.g. use of relevant biomarkers) for predicting the aging trajectory or overall pathogenesis of disease;
- Use of cutting-edge technologies taking into account aging-driven phenomena.

Research focus:

1. Standard research projects: the effect of aging on human health
Proposals are invited addressing diverse effects of aging on human health, exploring the basic mechanisms underlying aging-related disease. The research proposals can address these issues using a broad range of biological organisational levels and scales, from molecular to cellular, tissues to organs and the entire organism and its environment. Multidisciplinary research plans based on synergizing collaborations between the partnering researchers are recommended.

2. Precision Medicine and big data in aging research
BIRAX is also interested in proposals researching the use of big data and precision medicine in relation to aging. In particular, we are interested in precision diagnostics and personalized effects of treatments specifically for older subjects, preventive measures and predictive analytics for older populations. Research proposals that contain a central "omics" component (e.g. genomics, epigenomics, transcriptomics, proteomics, metabolomics) are encouraged.

Specific research priorities:

1. The effect of aging on human health: preventive, disease modifying and regenerative medicine approaches to medical conditions and the aging process.
Proposals under this category must be relevant to at least one of these priorities: cardiovascular disease, diabetes, neurodegenerative conditions, arthritis and other musculoskeletal disorders, age-related frailty and other geriatric syndromes, and age-related multimorbidity.

2. Aging and Technology: Precision medicine and big data in aging research.
Proposals under this theme will aim to identify innovative biomarkers, algorithms, computational and measurement techniques and to promote advances in precision medicine that would allow the prevention or mitigation of age-related conditions or harmful effects associated with aging. Proposals that build on effective collaboration between basic and clinical research and big data and those facilitating the translation of basic research to clinical practice will be prioritized.

GrantWatch ID#:

GrantWatch ID#: 138648

Estimated Size of Grant:

Grants of a value up to £400,000 over three years.

Term of Contract:

Research proposals should be for 36 months in duration.

Additional Eligibility Criteria:

1. Proposals must be submitted by two Principal Investigators; one resident in the UK and the other in Israel. Both must be employed in an academic institution, research hospital or research institution in the country in which they are resident.

2. Principle Investigators are expected to be established researchers who have progressed in their research careers, supervised students and managed grant funding. Allowances can be made for career breaks or other extenuating circumstances.

3. Principal Investigators must hold a position in academic institutions, research hospitals and research institutions in the UK or in Israel, that are officially recognized by both countries.

4. Proposals may include a partner from a third country, however BIRAX will fund the activity of the British and Israeli labs only.

5. Applications must include a joint research program in the form of a single, coordinated application, in which the roles and tasks of the respective partners are clearly defined.

6. Multiple applications from institutions are acceptable, however, each principal investigator may submit only one application in this call for proposals.

7. Principal Investigators of previous and current BIRAX funded projects are eligible to apply but not with the same partner and not as an extension of previously funded work.

8. Principles Investigators of running BIRAX funded projects are eligible to apply only providing that their current project will end by the time the new project is expected to start (circa May 2019). Projects running in parallel will not be funded.

9. At the preliminary proposal stage it is not necessary for the application to be signed by senior authorized personnel from the participating institutions i.e. Deans of Faculty in the UK and the University Research Authority in Israel. This will be a requirement for projects that are asked to submit full proposals.

The scheme is not intended to simply supplement ongoing research. Neither is it intended to meet any perceived shortfalls in existing project funding from other donors, or to simply “top up” funding shortages for postgraduate students, research assistants or others working for the applicant(s).

Pre-proposal Conference:

On the first week of September 2018, the British Council and Kings College London will hold two academic conferences in connection with the Call for Proposals:

- 3 - 4 September 2018: Precision Medicine in Ageing
- 4 - 6 September 2018: BIRAX Conference on Ageing

Both conferences will be held at Guy’s Hospital Campus, King’s College London and will provide ample opportunities for networking for the purpose of finding a partner for submission.

For more information about the BIRAX conference, please visit http://www.ageing2018.org/.

Pre-Application Information:

Timeline:
- Call for proposal launched: May 30, 2018
- Deadline for pre-proposal applications: October 15, 2018, 22:00 GMT
- Response letters sent out: End of December 2018
- Full proposal deadline: Mid-February 2019
- Response letters sent out: April 2019
- Announcement of successful projects: July 2019

Successful applicants whose proposals have been shortlisted by the BIRAX Ageing selection panel will be invited to submit a full application.

Contact Information:

Before starting your grant application, please review the funding source's website listed below for updates/changes/addendums/conferences/LOIs.

Apply online: https://www.eventsforce.net/britishcouncil/1518/register

BIRAX
Sason Hogi Tower
12 Abba Hillel Road
PO Box 3302
Ramat Gan 52506

biraxrmi@britishcouncil.org.il

URL for Full Text (RFP):

Geographic Focus:

Israel

International country outside of the USA, Israel and Canada.