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2017 Million Dollar Bike Ride (MDBR) Pilot Grant

Grants to USA Academic Faculty and
Individuals for Rare Disease Research

Agency Type:

Foundation / Corporation

Funding Source:

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Penn Medicine - Orphan Disease Center (ODC)

LOI Date:


Deadline Date:

10/18/17 8:00 PM EST


Request a Grant Writer

Grants of up to $71,000 to USA academic faculty or individuals holding senior scientific positions at nonprofits for research projects and case studies on selected diseases. LOIs must be submitted by September 18, 2017. The grants focus is on 22 rare diseases, with 1-2 grants per disease. See RFP below for full details and funding amounts for each disease category.

The grant covers the following expenses only:
- Salary for PI
- Salary/stipend and related benefits for graduate student/postdoctoral fellow/technical support
- Travel (up to $1,500)
- Laboratory supplies and other research expenses
- IDCs of 10% are included in the total award amount

If accepted to submit a full application, the following criteria will be used to judge the proposal:

- Project Proposal. Is the proposed project of high scientific quality? Is the budget fully justified and reasonable in relation to the proposed project?

- Background – Is the fundamental objective of the study and hypothesis to be addressed clearly defined?

- Scientific Approach - Will the proposed specific aims answer the study hypothesis? Will the scientific approach effectively test and answer each specific aim? Are the study goals supported by existing data?

- Clinical Impact - Is the answer to the study hypothesis important to our ability to treat or reduce rare disorders/disease incidence and/or mortality? Will the proposed research lead to substantial advances and/or contribute to large leaps of understanding or knowledge that will contribute to reductions in disease incidence and/or mortality within the decade?

- Research Significance - Does the study address an important question that is not likely to be addressed without this funding? Does the proposed study offer a unique opportunity to explore an important issue and/or employ a novel approach to this disease research? Will the study outcomes advance our knowledge of this disease and/or contribute to changes in the focus of future research questions or the way we conduct research on this issue?

- Investigator Qualifications – Does the investigator hold a track record of outstanding accomplishment as evidenced by peer-reviewed publications and funding awards? Does the investigator have access to the resources and environment necessary to complete the study as outlined?

GrantWatch ID#:

GrantWatch ID#: 160999

Number of Grants:


Estimated Size of Grant:

Number of awards and dollar amounts vary per disease based on fundraising totals by each disease team.

Term of Contract:

Award will be for one year. The proposed funding period will run from Jan 1, 2018, through Dec 31, 2018.

Additional Eligibility Criteria:

All individuals holding a faculty‐level appointment at an academic institution or a senior scientific position at a nonprofit institution or foundation are eligible.

The following are not covered by the grant:
- Salary/consultant costs
- Tuition
- Professional membership dues
- Equipment >$5,000
- General office supplies, institutional administrative charges (e.g., telephone, other electronic communication, IT network, etc.)
- Pre‐award charges
- Any other expenses not directly related to the project

Pre-Application Information:

The deadline for submission of LOIs is September 18, 2017 at 8:00 PM EST. Full Application is by Invitation only after review of Pre-Application. Proposal due date is Wednesday, October 18, 2017, no later than 8:00 PM EST.

Funds will be issued through cost reimbursement mechanism executed by purchase order from the University of Pennsylvania.

Contact Information:

Before starting your grant application, please review the funding source's website listed below for updates/changes/addendums/conferences/LOIs.

Submit an LOI:

Full application documents are to be uploaded at

For questions regarding the scientific content of potential projects:
Monique Molloy

For administrative queries:
Samantha Charleston

University of Pennsylvania
304K Lynch Laboratories
Philadelphia, PA 19104

URL for Full Text (RFP):

Geographic Focus:

USA: Alabama;   Alaska;   Arizona;   Arkansas;   California;   Colorado;   Connecticut;   Delaware;   Florida;   Georgia;   Hawaii;   Idaho;   Illinois;   Indiana;   Iowa;   Kansas;   Kentucky;   Louisiana;   Maine;   Maryland;   Massachusetts;   Michigan;   Minnesota;   Mississippi;   Missouri;   Montana;   Nebraska;   Nevada;   New Hampshire;   New Jersey;   New Mexico;   New York City;   New York;   North Carolina;   North Dakota;   Ohio;   Oklahoma;   Oregon;   Pennsylvania;   Rhode Island;   South Carolina;   South Dakota;   Tennessee;   Texas;   Utah;   Vermont;   Virginia;   Washington, DC;   Washington;   West Virginia;   Wisconsin;   Wyoming