Target Advancement Program

Grants to USA, Canada, and International Universities,
Nonprofits, and For-Profits for Research on Parkinson's Disease

GrantWatch ID#: 170931
Agency Type:

Foundation / Corporation

The Michael J. Fox Foundation (MJFF)




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Grants to USA, Canada, and International university labs, for-profit companies, and nonprofit research institutions for research projects that will lead to new developments in treating Parkinson's disease. The funding source seeks to build robust evidence to rationalize biological pathways and targets for further translation into new Parkinson's treatments.

Target Advancement Awards support research characterizing promising, novel PD-relevant targets or continuing target biology work on established PD targets. Preferred targets for this program already demonstrate links to PD in human patient populations. These awards are well-suited to projects where hypothetical or experimental rationale for a target is compelling but limited, and study results can make the case for continuing (or discontinuing) a line of research. The Foundation invites projects designed to assess emerging PD targets in pre-clinical models, human cellular models, and human tissue and fluid matrices.

Research Models:

The Foundation invites projects designed to assess emerging PD targets in pre-clinical models, human cellular models, and human tissue and fluid matrices. Funding requests to support use of biosamples from these resources will be considered by the Foundation on a case-by-case basis.

Biological Mechanisms:

Target Advancement Awards also support projects addressing roadblocks and knowledge gaps in understanding biological mechanisms associated with established PD targets already supported by a strong body of validation data: alpha-synuclein, LRRK2, GBA, Nurr1, Parkin/PINK1, and trophic factors. Proposals will be reviewed in the context of existing MJFF investments in these areas.

The Foundation will consider the following criteria when selecting proposals to fund:

The Foundation looks for scientifically compelling, logical, and well-crafted research proposals that offer real potential for improving treatments for people with Parkinson's disease. In general, proposals are reviewed along a number of key factors, including responsiveness to the specific funding program, scientific rationale, experimental design, investigator expertise, and overall feasibility.


Target Advancement Awards are one-year grants.

The Foundation funds grants in labs around the world in order to engage researchers with a broad range of expertise and promising ideas.

The Foundation does not limit its funding to academic labs. Funding is provided to university labs, for-profit companies, and nonprofit research institutions.

Informational Webinar:

Date: September 7, 2017
Time: 12 pm - 1 pm EDT

This webinar provides an overview of MJFF's funding strategy, MJFF's funding opportunities and how to apply for funding and the review process.

Click on the link below to register for the informational webinar.

Please note: MJFF has launched a Targeted Pathway RFA for Mitochondrial Biomarkers. Proposed projects focusing on non-biomarker related mitochondrial target validation should apply to MJFF's Target Advancement core funding program and not the Mitochondrial Biomarkers Targeted RFA program.

Deadlines for Spring 2018 Cycle:

- Pre-Proposals Due: September 27, 2017 - 5pm US ET
- Full Proposal Invitations: December 2017
- Full Proposals Due (by invite only): January 23, 2018 - 5pm US ET
- Anticipated Award Announcement: April 2018
- Anticipated Funding: May 2018

Click here for more information:


Before starting your grant application, please review the funding source's website listed below for updates/changes/addendums/conferences/LOIs.

Click here to register for the informational webinar on September 7th:

Click here to apply online:

Please direct inquiries regarding programmatic, fiscal and administrative issues to

Note: Please email for more information related to biosample requests and resource availability.

Additional Contact Information:

The Michael J. Fox Foundation for Parkinson's Research
Grand Central Station
P.O. Box 4777
New York, NY 10163-4777

Toll-free: 1-800-708-7644

See the full text of this grant

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International country outside of the USA, Israel and Canada.

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