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Investigator Initiated Research Projects (IIRP) and Innovative, Developmental or Exploratory Activities (IDEA) in Stem Cell Research (Rd 6)

Contracts for Services to New York Nonprofits and
Agencies for Biological Research

Agency Type:


Funding Source:

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New York State Department of Health (DOH) and Empire State Stem Cell Board (ESSCB)

Conf. Date:


LOI Date:


Deadline Date:

06/25/20 4:00 PM


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Contracts for services to New York nonprofit organizations and government agencies to conduct specific biological research. Funding is intended to support basic, applied, translational, pre-clinical, and clinical scientific studies related to any aspect of stem cell biology. The goal of the program is to better understand the unique properties of stem cells and to allow their utilization to treat disease. Eligible organizations are invited to submit applications for the following funding mechanisms: 1. Investigator Initiated Research Project (IIRP); and 2. Innovative, Developmental or Exploratory Activities (IDEA).

The ESSCB is interested in supporting established and early career stage investigators from applicant organizations. Investigators can include those new to the field of stem cell research and those in disciplines that have not historically focused on stem cell research. Although collaborations are not required, they are strongly encouraged. Research studies that promote translation of stem cell science to therapeutic applications are encouraged.

The Investigator Initiated Research Project mechanism is designed to:

  • Investigate a well-developed problem or research hypothesis; or
  • Develop technologies or resources that are essential to overcome existing barriers to progress toward therapeutic applications.
  • An application for this mechanism should include robust preliminary data.

The IDEA mechanism is designed to:

  • Open a new area of investigation; or
  • Test a novel or innovative hypothesis; or
  • Produce viable data for preparation of a full-scale research application; or
  • Apply or develop state-of-the-art technologies, tools or resources for stem cell research.
  • An application for this mechanism should be highly speculative, exploratory, or high-risk and have the potential for high scientific payoff (with or without pilot data). IDEA awards are not intended to fund smaller components of larger Investigator Initiated Research Projects, or for compression of a larger project into a smaller time frame. However, it is the intent of the ESSCB that successful IDEA projects will be eligible to apply for future IIRP awards.

Applicants may subcontract components of the scope of work. For those applicants that propose subcontracting, it is necessary to identify subcontracting agencies during the application process. Subcontracting and collaborating organizations may include public, not-for-profit and for-profit entities within or outside of New York State.

Together with  (the New York State Stem Cell Science Program (NYSTEM), the ESSCB makes funding recommendations for creative and innovative biomedical research projects to be supported by the Empire State Stem Cell Trust Fund. Information about the ESSCB and NYSTEM can be found at

GrantWatch ID#:

GrantWatch ID#: 171312

Estimated Total Program Funding:


Number of Grants:

Approximately 70 awards

Estimated Size of Grant:

- IIRP: Annual direct costs are capped at $300,000.
- IDEA: Annual direct costs are capped at $150,000, with a maximum of $275,000 in direct costs to be spent over the two-year period.

Term of Contract:

IIRP: Contract term will be up to three years
IDEA: Contract term will be up to two years

Additional Eligibility Criteria:

The applicant must be a not-for-profit organization or governmental organization in New York State. Awarded organizations will be expected to monitor the use of funds, maintain individual accounts and fulfill other fiscal management criteria. Subcontracting and collaborating organizations
may include public, not-for-profit and for-profit entities within or outside of New York State.

The eligible Principal Investigator (PI) is designated by the application organization, has the skills, knowledge, and resources necessary to carry out the proposed Workplan, and is not a postdoctoral fellow or other dependent research staff.

Each eligible PI is limited to one application for each funding mechanism (IIRP and IDEA).

The PI is not restricted from receiving Public Health Service (PHS) funding or debarred by the United States Food and Drug Administration (FDA) or any other federal or New York State government entity.

Pre-proposal Conference:

Potential applicants are strongly encouraged to participate in the applicant conference to receive an overview of the RFA and ask specific questions.

Applicant Conference Registration Due: February 25, 2020

Applicant Conference: February 26, 2020, at 10:30 AM EST
By Webinar (WebEx) at: 1-844-633-8697 or 1-518-549-0500
Meeting ID # 649 845 467

Applicants unable to participate in the webinar will have the option to view the applicant conference slides at their convenience.

Pre-Application Information:

Optional letters of intent (strongly encouraged) are due by March 3, 2020.

Questions are due by March 10, and answers will be posted on March 17.

Applications are due byJune 25, 2020, 4:00 PM EST. The applicant organization must be Prequalified in the NYS Grants Gateway, if not exempt.

Prospective grantees are strongly encouraged to submit their applications at least 48 hours prior to the due date and time.

View this opportunity on Grants Gateway:

Contact Information:

Before starting your grant application, please review the funding source's website listed below for updates/changes/addendums/conferences/LOIs.

Apply online on Grants Gateway:

Submit questions to:
Andrea Garavelli, Extramural Grants Administration
New York State Department of Health
Wadsworth Center, Empire State Plaza, Room C345
PO Box 509
Albany, NY 12201-0509
(518) 474-7002

Grants Gateway Support:

Funding or Pin Number:

Request for Applications #18373. Grants Gateway ID: DOH01-STEM6-201

URL for Full Text (RFP):

Geographic Focus:

USA: New York City;   New York

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