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CDMRP PRMRP Discovery Award

Grants to USA, Canada, and International Investigators and Organizations
and USA Agencies for Research Associated with Health in the Military

Agency Type:


Funding Source:

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U.S. Department of Defense (DoD) - U.S. Army Medical Research Acquisition Activity (USAMRAA)

LOI Date:


Deadline Date:

05/13/21 11:59 PM ET


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Grants to USA, Canada, and International investigators and organizations and USA government agencies for medical research associated with health in the military. Applicants are required to submit a pre-application prior to submitting a full application. Required registrations may take several weeks to complete. A wide range of eligible areas of health will be considered.

All applications for PRMRP funding must specifically address at least one of the Topic Areas as directed by Congress and have direct relevance to military health. Topic Areas are listed below.

  • Arthritis
  • Burn Pit Exposure
  • Cardiomyopathy
  • Congenital Heart Disease
  • Diabetes
  • Dystonia
  • Eating Disorders
  • Emerging Viral Diseases
  • Endometriosis
  • Epidermolysis Bullosa
  • Familial Hypercholesterolemia
  • Fibrous Dysplasia
  • Focal Segmental Glomerulosclerosis
  • Food Allergies
  • Fragile X
  • Frontotemporal Degeneration
  • Hemorrhage Control
  • Hepatitis B
  • Hydrocephalus
  • Hypertension
  • Inflammatory Bowel Diseases
  • Malaria
  • Metals Toxicology
  • Mitochondrial Disease
  • Myalgic Encephalomyelitis/Chronic Fatigue Syndrome
  • Myotonic Dystrophy
  • Non-Opioid Therapy for Pain Management
  • Nutrition Optimization
  • Pathogen-Inactivated Blood Products
  • Peripheral Neuropathy
  • Plant-Based Vaccines
  • Platelet-Like Cell Production
  • Polycystic Kidney Disease
  • Pressure Ulcers
  • Pulmonary Fibrosis
  • Respiratory Health
  • Rheumatoid Arthritis
  • Sleep Disorders and Restriction
  • Suicide Prevention
  • Sustained Release Drug Delivery
  • Vascular Malformations
  • Women’s Heart Disease

The intent of the PRMRP Discovery Award is to support innovative, non-incremental, high-risk/potentially high-reward research that will provide new insights, paradigms, technologies,
or applications. Studies supported by this award are expected to lay the groundwork for future avenues of scientific investigation. The proposed research project should include a well-formulated, testable hypothesis based on a sound scientific rationale and study design.  

Relevance to the healthcare needs of military Service Members, Veterans, military beneficiaries, and/or the American public is a key feature of this award. Applications are required to include an explanation of how the proposed project has relevance to military health. Applicants are encouraged to integrate and/or align their research projects with DOD and/or VA research laboratories and programs. Collaboration with DOD or VA investigators is also encouraged.

For this award mechanism, direct costs may be requested for (not all-inclusive):

  • Support for multidisciplinary collaborations, including travel
  • Travel costs for one investigator to travel to one scientific/technical meeting per year. 

GrantWatch ID#:

GrantWatch ID#: 195329

Estimated Total Program Funding:


Number of Grants:

Approximately 75 Discovery Award applications.

Estimated Size of Grant:

- The anticipated direct costs budgeted for the entire period of performance for an FY21 PRMRP
Discovery Award will not exceed $200,000.
- Funding of applications received is contingent upon the availability of federal funds for this program as well as the number of applications received, the quality and merit of the applications as evaluated by scientific and programmatic review, and the requirements of the government.

Term of Contract:

- The maximum period of performance is 2 years.
- The applicant may request the entire maximum funding amount for a project that may have a period of performance less than the maximum 2 years

Additional Eligibility Criteria:

Eligible Applicants:
Organizations: All organizations, including foreign organizations, foreign public entities, and international organizations, are eligible to apply.

Government Agencies Within the United States: Local, state, and federal government agencies are eligible to the extent that applications do not overlap with their fully funded internal programs. Such agencies are required to explain how their applications do not overlap with their internal programs.

As applications for this program announcement may be submitted by extramural and intramural
organizations, these terms are defined here:

Principal Investigator:
- Investigators at the level of postdoctoral fellow or clinical fellow (or equivalent) and above may be named by the organization as the PI on the application.
- There is no limitation on the number of applications for which an investigator may be named by the organization as a PI.
- An eligible PI, regardless of ethnicity, nationality, or citizenship status, must be employed by, or affiliated with, an eligible organization.

Organizations must be able to access .gov and .mil websites in order to fulfill the financial and technical deliverable requirements of the award and submit invoices for payment.

Funds must not be requested for tuition.

Research involving animals, human subjects, and human anatomical substances is permitted; however, this award may not be used to conduct clinical trials.

Pre-Application Information:

Submission and Review Dates and Times:
- Pre-Application Submission Deadline: 5:00 PM Eastern time (ET), April 29, 2021
- Application Submission Deadline: 11:59 PM ET, May 13, 2021
- End of Application Verification Period: 5:00 PM ET, May 18, 2021
- Peer Review: July 2021
- Programmatic Review: August/September 2021

Awards supported with FY21 funds are anticipated to be made no later than September 30, 2022.

Submission of applications that are essentially identical or propose essentially the same research project to different funding opportunities within the same program and fiscal year is prohibited and will result in administrative withdrawal of the duplicative application(s).
Extramural Submission:
- Pre-application content and forms must be accessed and submitted at
- Full application packages must be accessed and submitted at

Intramural DOD Submission:
- Pre-application content and forms must be accessed and submitted at
- Full application packages must be accessed and submitted at Note: Applications from an intramural DOD organization or from an extramural federal government organization may be submitted to through a research foundation.

Submission of application information includes assignment of primary and secondary research classification codes:
For further application information requirements, see:

Dun and Bradstreet Data Universal Numbering System (DUNS) Number and System for Award Management (SAM): Applicant organizations and all sub-recipient organizations must have a DUNS number to submit applications to The applicant organization must also be registered in the Entity Management functional area of the SAM with an “Active” status to submit applications through the portal. Verify the status of the applicant organization’s Entity registration in SAM well in advance of the application submission deadline. Allow several weeks to complete the entire SAM registration process.

Through April 2022, a transition from DUNS to the SAM-generated UEI will occur. Refer to the General Application Instructions, Section III.1, DUNS Number, for more information on the transition and timing.

View this opportunity on

For a list of application documents, go to the Package tab (press Preview) on the link above.

Contact Information:

Before starting your grant application, please review the funding source's website listed below for updates/changes/addendums/conferences/LOIs.


CDMRP Help Desk: or 301-682-5507 Contact Center: or 800-518-4726; International 1-606-545-5035

CFDA Number:


Funding or Pin Number:


URL for Full Text (RFP):

Geographic Focus:

USA: Alabama;   Alaska;   Arizona;   Arkansas;   California;   Colorado;   Connecticut;   Delaware;   Florida;   Georgia;   Hawaii;   Idaho;   Illinois;   Indiana;   Iowa;   Kansas;   Kentucky;   Louisiana;   Maine;   Maryland;   Massachusetts;   Michigan;   Minnesota;   Mississippi;   Missouri;   Montana;   Nebraska;   Nevada;   New Hampshire;   New Jersey;   New Mexico;   New York City;   New York;   North Carolina;   North Dakota;   Ohio;   Oklahoma;   Oregon;   Pennsylvania;   Rhode Island;   South Carolina;   South Dakota;   Tennessee;   Texas;   Utah;   Vermont;   Virginia;   Washington, DC;   Washington;   West Virginia;   Wisconsin;   Wyoming

USA Territories: American Samoa (USA)   Guam (USA)   Puerto Rico (USA)   Virgin Islands (USA)   Northern Mariana Islands (USA)

USA Compact Free Associations: The Federated States of Micronesia (USA)   Marshall Islands (USA)   Republic of Palau (USA)

Canada: Alberta;   British Columbia;   Manitoba;   New Brunswick;   Newfoundland and Labrador;   Northwest Territories;   Nova Scotia;   Nunavut;   Ontario;   Prince Edward Island;   Quebec;   Saskatchewan;   Yukon;


International country outside of the USA, Israel and Canada.

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