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Cooperative Agreements to USA, Canada, and International Nonprofits, For-Profits, IHEs, Agencies, and Individuals to Improve Biomedical Data Storage Systems

Biomedical Data Repository

GrantWatch ID# 207290
Agency: Federal

Funding Source
National Institute of Health (NIH) - National Institute of Neurological Disorders and Stroke (NINDS)
CFDA Number: 93.113
Funding or PIN Number: PAR-23-079
Array ( [0] => American Samoa (USA); [1] => Guam (USA); [2] => Puerto Rico (USA); [3] => Virgin Islands (USA); [4] => Northern Mariana Islands (USA); )

Geographic Focus
USA Territories: American Samoa (USA);   Guam (USA);   Puerto Rico (USA);   Virgin Islands (USA);   Northern Mariana Islands (USA);
USA Compact Free Associations:The Federated States of Micronesia (USA)   Marshall Islands (USA)   Republic of Palau (USA)
Canada:Alberta;   British Columbia;   Manitoba;   New Brunswick;   Newfoundland and Labrador;   Northwest Territories;   Nova Scotia;   Nunavut;   Ontario;   Prince Edward Island;   Quebec;   Saskatchewan;   Yukon;
International, Israel and Canada.

Important Dates
Deadline: 01/25/23 5:00 PM Local Time

Grant Description
Cooperative agreements to USA, Canada, and International nonprofit and for-profit organizations, IHEs, government agencies, Tribal agencies, and individuals to improve the efficiency of biomedical data storage systems. Applicants are advised that required registrations must be completed prior to applying. Certain applicants must contact the funding source prior to applying.

Accessible, well-maintained, and efficiently operated data resources are critical enablers of modern biomedical research. Data resources, through good data management practices, are the key to data and knowledge discovery, integration, and data reuse, as outlined by the FAIR Data Principles (Findable, Accessible, Interoperable, and Reusable digital objects). In order to sustain a healthy and productive data resource ecosystem, it is critical to ensure that each component: (a) delivers scientific impact to the communities that they serve; (b) employs and promotes good data management practices and efficient operation for quality and services; (c) engages with the user community and continuously address their needs; and (d) supports a process for data life-cycle analysis, long-term preservation, and trustworthy governance.

In order to better support such a modern data resource ecosystem, NIH makes a distinction between data repositories and knowledgebases. While each activity is important for advancing biomedical research, data repositories and knowledgebases can have unique functions, metrics for success and sustainability needs. Biomedical data repositories accept submission of relevant data from the community to store, organize, validate, archive, preserve and distribute the data, in compliance with the FAIR Data Principles. Biomedical knowledgebases on the other hand extract, accumulate, organize, annotate, and link the growing body of information that is related to and relies on core datasets. The funding announcement for Biomedical knowledgebases is at PAR-23-078.

This funding opportunity announcement supports the biomedical data repositories that are important to the mission of the NIH Institutes and Centers participating in this announcement. The evaluation of the repositories will empasize their utility and impact, quality of data and services and efficiency of operations, community needs and engagement, trustworthiness of stewardship and governance .

Biomedical data repositories under this announcement should have the primary function to ingest, archive, preserve, manage, distribute, and make accessible the data related to a particular system or systems. Support for data curation must be limited to that which improves the efficiency and accessibility of data ingestion, management, and use and reuse by the user communities. Support for software and tool development must be limited to that which provides essential functions or significantly increases the efficiency of operation of the repository.


  • City or township governments
  • County governments
  • For profit organizations other than small businesses
  • Independent school districts
  • Native American tribal governments (Federally recognized)
  • Native American tribal organizations (other than Federally recognized tribal governments)
  • Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
  • Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
  • Private institutions of higher education
  • Public and State controlled institutions of higher education
  • Public housing authorities/Indian housing authorities
  • Others (see text field entitled "Additional Eligibility Criteria" for clarification)
  • Small businesses
  • State governments

Additional Criteria for Eligibility
Eligible Organizations

Higher Education Institutions:
- Public/State Controlled Institutions of Higher Education
- Private Institutions of Higher Education

The following types of Higher Education Institutions are always encouraged to apply for NIH support as Public or Private Institutions of Higher Education:
- Hispanic-serving Institutions
- Historically Black Colleges and Universities (HBCUs)
- Tribally Controlled Colleges and Universities (TCCUs)
- Alaska Native and Native Hawaiian Serving Institutions
- Asian American Native American Pacific Islander Serving Institutions (AANAPISIs)

Nonprofits Other Than Institutions of Higher Education
- Nonprofits with 501(c)(3) IRS Status (Other than Institutions of Higher Education)
- Nonprofits without 501(c)(3) IRS Status (Other than Institutions of Higher Education)

For-Profit Organizations
- Small Businesses
- For-Profit Organizations (Other than Small Businesses)

Local Governments
- State Governments
- County Governments
- City or Township Governments
- Special District Governments
- Indian/Native American Tribal Governments (Federally Recognized)
- Indian/Native American Tribal Governments (Other than Federally Recognized)

Eligible Agencies of the Federal Government
- Independent School Districts
- Public Housing Authorities/Indian Housing Authorities
- Native American Tribal Organizations (other than Federally recognized tribal governments)
- Faith-based or Community-based Organizations
- Regional Organizations
- Non-domestic (non-U.S.) Entities (Foreign Institutions)

Foreign Institutions
- Non-domestic (non-U.S.) Entities (Foreign Institutions) are eligible to apply.
- Non-domestic (non-U.S.) components of U.S. Organizations are eligible to apply.
- Foreign components, as defined in the NIH Grants Policy Statement, are allowed.

Eligible Individuals (Program Director/Principal Investigator):
Any individual(s) with the skills, knowledge, and resources necessary to carry out the proposed research as the Program Director(s)/Principal Investigator(s) (PD(s)/PI(s)) is invited to work with his/her organization to develop an application for support. Individuals from diverse backgrounds, including underrepresented racial and ethnic groups, individuals with disabilities, and women are always encouraged to apply for NIH support.

Clinical trials are not allowed. Only applications that do not propose clinical trials will be accepted.

NIH will not accept:
- A new (A0) application that is submitted before issuance of the summary statement from the review of an overlapping new (A0) or resubmission (A1) application.
- A resubmission (A1) application that is submitted before issuance of the summary statement from the review of the previous new (A0) application.
- An application that has substantial overlap with another application pending appeal of initial peer review

Applications that have a significant focus on software and tool development are not appropriate for this activity.

Pre-Application Information
Application deadline: January 25, 2023
All applications are due by 5:00 PM local time of applicant organization.

Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.

Applicants requesting $500,000 or more in direct costs in any year (excluding consortium F&A) must contact a Scientific/ Research Contact at least 6 weeks before submitting the application and follow the Policy on the Acceptance for Review of Unsolicited Applications that Request $500,000 or More in Direct Costs as described in the SF424 (R&R) Application Guide.

Applicant organizations must complete and maintain the following registrations as described in the SF 424 (R&R) Application Guide to be eligible to apply for or receive an award. All registrations must be completed prior to the application being submitted:
- System for Award Management (SAM):
- NATO Commercial and Government Entity (NCAGE) Code – Foreign organizations must obtain an NCAGE code (in lieu of a CAGE code) in order to register in SAM:
- Unique Entity Identifier (UEI)- A UEI is issued as part of the registration process. The same UEI must be used for all registrations, as well as on the grant application.
- eRA Commons:

Applicant organizations may submit more than one application, provided that each application is scientifically distinct.

How to Apply - Application Guide:

View this opportunity on

For a list of application documents, go to the Package tab (press Preview) on the link above.

Term of Contract
Applications may request up to five years of support for a biomedical data repository.

Contact Information
Applicants must use one of these submission options to access the application forms for this opportunity.

1. Use the NIH ASSIST system to prepare, submit and track your application online:

2. Use an institutional system-to-system (S2S) solution to prepare and submit your application to and eRA Commons to track your application:

3. Use Workspace to prepare and submit your application and eRA Commons to track your application.

Application Submission Contacts:
Finding Help Online: (preferred method of contact)
Telephone: 301-402-7469 or 866-504-9552 (Toll Free)

General Grants Information (Questions regarding application instructions, application processes, and NIH grant resources)
Email: (preferred method of contact)
Telephone: 301-637-3015 Customer Support (Questions regarding registration and Workspace)
Contact Center Telephone: 800-518-4726

For Scientific/Research and other contacts, see the Full Grant Text RFP button.

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