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Grants to Canada Researchers Affiliated with Academic Institutions for Multiple Sclerosis Research

Discovery Research Grant Program

GrantWatch ID# 155614
Agency: Foundation

Funding Source
Multiple Sclerosis Society of Canada (MSSC)
Array ( )

Geographic Focus
Canada:Alberta;   British Columbia;   Manitoba;   New Brunswick;   Newfoundland and Labrador;   Northwest Territories;   Nova Scotia;   Nunavut;   Ontario;   Prince Edward Island;   Quebec;   Saskatchewan;   Yukon;

Important Dates
Deadline: 10/03/22 4:00 PM EDT Save

Grant Description
Grants to Canada individual researchers affiliated with academic institutions for expenses related to multiple sclerosis research projects. Funding is intended to support projects that improve care and treatment, advance understanding of the disease and stop its progression, prevent MS, and enhance the wellbeing of individuals affected by MS.

The Discovery Research Grant program is intended to support research operations that will help generate new scientific knowledge and improve the health and quality of life of people affected by MS. The Discovery Research Grant supports investigator-initiated research proposals and there are no topic restrictions imposed, other than the required demonstration of relevance to MS. Proposals should address research questions in one or more of the impact goal areas identified in the MSSC strategic plan:

  • Advance Treatment and Care: Research that aims to advance treatment and care for people affected by MS (e.g. symptom management; diagnosis; developing new treatments and understanding their mechanisms, understanding and evaluating interventions to address mental health, wellness/self-care, and rehabilitation in people living with MS; innovations in the provision of health services, clinical care practices and models of care; and advances in healthcare delivery/policy).
  • Enhance Well-being: Research that aims to understand how to enhance the well-being of people affected by MS within communities (e.g. understanding the social determinants of health; assessing the health economics/cost benefit analysis on MS interventions and support structures and systems; evaluation of community-based programs; and advances in health systems research/policy).
  • Understand and Halt Disease Progression: Research that aims to understand the etiology and mechanisms of MS, disease progression, progressive MS, and repair (e.g., myelin biology, neurobiology, neurophysiology, immunology, neuropathology, and imaging).
  • Prevent MS: Research that aims to prevent MS (e.g. identifying risk factors for disease, effective interventions for prevention, health economic/cost benefit analysis on prevention, and defining highest risk populations).

Based on the nature of the research, applicants can apply to one of the following two streams:

  • Biomedical Research Stream The Biomedical Research stream supports research which uncovers the biological, pathological, and mechanistic aspects of MS, and provides fundamental knowledge about the development, progression, prevention and treatment of MS disease. Studies can involve in vitro, animal, and/or human models.
  • Clinical and Population Health Research Stream The Clinical and Population Health Research stream supports clinical research with the goal of improving diagnosis, treatment, or the health and quality of life of individuals with MS; health services research; encompasses research on, or for the treatment of, people affected by MS; supports population health research that aims to understand the complex, biological, social, cultural and environmental interactions that determine the health of individuals and populations.

Grant Recipients may request funds for the following categories of expenditure: Salaries for personnel, patient costs, permanent equipment, consumable supplies, and travel. Discovery Research Grants may provide support for trainees (i.e. doctoral and master’s students and postdoctoral fellows) commensurate with the time they will spend on the research directly supporting the Grant. For additional information regarding eligible expenditures, see


  • Others (see text field entitled "Additional Eligibility Criteria" for clarification)

Additional Eligibility Criteria
Institutions are the official recipients of grants made for the support of specific research by the PI (Principal Investigator). MSSC only accepts applications from Canadian post-secondary institutions and their affiliated institutions including hospitals and research institutes.

The Principal Investigator is listed as the primary applicant/contact and is responsible for overseeing the research conducted as part of the proposal. The PI must be considered eligible by his or her institution to apply for a research grant. The PI does not have to be a Canadian citizen but must be conducting research in a Canadian institution which is recognized by the Tri-Council Agencies. The PI is autonomous regarding their research activities, has a faculty appointment that allows the individual to pursue the proposed research, and is equipped to supervise trainees and publish research activities.

For additional Eligibility Criteria for Co-PI, Co-Applicant, and Collaborator, see

For ineligible expenditures, see

Pre-Application Information
- Competition Opens:   July 28, 2022
- Application Deadline: October 3, 2022 at 16:00 EDT
- Anticipated Notice of Decision: March 2023
- Funding Start Date: April 1, 2023

The PI may concurrently submit a maximum of one (1) new Catalyst Research Grant application and one (1) Discovery Research Grant application per competition. The PI can hold a maximum of two (2) Discovery Research Grants and one (1) Catalyst Research Grant at any one time. Data and outcomes that will be derived from the Catalyst Research Grant should not overlap with those from a Discovery Research Grant, but the topics can be related.

Applications that were unsuccessful in their previous submission to the MSSC Discovery Research Grant competition are considered resubmissions. Resubmitting an application is permitted.

Applicants are required to connect their ORCiD identifier, a persistent and unique digital identifier, to the ProposalCentral profile. ORCiD will connect your iD with your professional information (e.g., grants, publications, funding, etc.):

Estimated Size of Grant
- The amount that may be requested is expected to be within a range of $50,000-$100,000 per year.
- Budgets may not exceed a maximum value of $ 300,000.

Term of Contract
Term of Funding: The MSSC supports Discovery Research Grants for up to three (3) years. These grants are non-renewable.
- Support beyond the maximum term of funding for a Discovery Research Grant (i.e. 3 years) will require submission of a new grant application that will be subject to review in direct competition with other new grant applications.

Contact Information
Online application portal:

Please direct all inquiries to

For questions related to site technical support, contact ProposalCentral customer support at:
800-875-2562 (Toll-free U.S. and Canada) or by email at

Multiple Sclerosis Society of Canada Research Department
250 Dundas Street West - Suite 500
Toronto, Ontario M5T 2Z5

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