Find Nonprofit and Small Business Grants

Advance Search

Only Available for Paid Subscribers
Clear Filters
Search Filters
Grants to USA, Canada, and International
Researchers for Research on Rare Diseases

2021 Million Dollar Bike Ride (MDBR) Pilot Grant Program

Agency Type:

Foundation / Corporation

Funding Source:

Add to My Calendar 

University of Pennsylvania School of Medicine - Orphan Disease Center (ODC)

LOI Date:


Deadline Date:

10/18/21 8:00 PM EST


Request a Grant Writer

Grants to USA, Canada, and International faculty-level academic researchers and senior scientific researchers at nonprofit institutions for medical research related to rare diseases. Applicants must submit a letter of inquiry prior to submitting a full proposal. Funding is intended to support research related to a rare disease represented in the 2021 Million Dollar Bike Ride.

Research Areas for the 2021 MDBR Grant Program:

  1. Adult Polyglucosan Body Disease (APBD)
  2. Ataxia-Telangiectasia (A-T)
  3. BPAN- A Neurodegeneration with Brain Iron Accumulation Disorder
  5. Castleman Disease
  6. CDKL5 Deficiency Disorder
  7. Choroideremia (CHM)
  8. Complex Lymphatic Anomalies (CLA)
  9. Congenital Hyperinsulinism (CHI)
  10. Congenital Muscular Dystrophy (CMD)
  11. Cohen Syndrome (COH)
  12. Nonsense Mutations in Cystic Fibrosis
  13. Dyskeratosis Congenita & Telomere Biology Disorder
  14. Fibrous Dysplasia/McCune Albright Syndrome
  15. Fibrodysplasia Ossificans Progressiva (FOP)
  16. Glut1 Deficiency Sundrome
  17. Lymphangioleiomyomatosis (LAM)
  18. Mucopolysaccharidoses (MPS)
  19. MPS Gene Spotlight: Mucopolysaccharidosis (MPS I)
  20. Maple Syrup Urine Disease (MSUD)
  21. Mitochondrial Complex 1 Deficiency Disorder - NUBPL
  22. Mucolipidosis Type IV (ML4)
  23. Neuroendocrine cell Hyperplasia of Infancy (NEHI)
  24. Niemann Pick Type C (NPC)
  25. Pitt Hopkins Syndrome (PTHS)
  26. RASopathies
  27. SETBP1 Disorder
  28. Snyder-Robinson Syndrome (SRS)
  29. STXBP1 Encephalopathy
  30. TBCK Syndrome

Allowable direct costs:

  • Salary for PI
  • Salary/stipend and related benefits for graduate student/postdoctoral fellow/technical support
  • Travel (up to $1,500)
  • Laboratory supplies and other research expenses
  • IDCs of 10% are included in the total award amount

More information about Research Focus Areas for Pilot Grants can be found at

GrantWatch ID#:

GrantWatch ID#: 160999

Number of Grants:

The number of grants depends on the research area. See page 2 of the RFA in Supporting Documents below for a list of total grants.

Estimated Size of Grant:

The total budget depends on the research area. See page 2 of the RFA in Supporting Documents below for a list of total funds.

Term of Contract:

This is a one year grant.

Additional Eligibility Criteria:

All individuals holding a faculty‚Äźlevel appointment at an academic institution or a senior scientific position at a non-profit institution or foundation are eligible to respond to this RFA.

Unallowable costs:
- Consultation costs
- Tuition
- Professional membership dues
- Equipment >$5,000
- General office supplies, institutional administrative charges (e.g. telephone, other electronic communication, IT network, - etc. )
- Pre-award charges
- Any other expenses not directly related to the project

Pre-Application Information:

LOI Due Date: Thursday, September 16, 2021 no later than 8pm (EST)

NOTE: Full Application is by invitation only after review of Pre-Application

Proposal Due Date: Monday, October 18, 2021 no later than 8pm (EST) Full application documents are to be uploaded on the website, by invitation only.

Funds will be issued through a cost reimbursement mechanism executed by purchase order from the University of Pennsylvania.

Million Dollar Bikeride:

Contact Information:

Before starting your grant application, please review the funding source's website listed below for updates/changes/addendums/conferences/LOIs.

Submit LOI online:

For any administrative inquiries regarding this grant please email Samantha Charleston at

University of Pennsylvania
TRL Suite 1200
125 South 31st Street
Philadelphia, PA 19104

URL for Full Text (RFP):

Geographic Focus:

USA: Alabama;   Alaska;   Arizona;   Arkansas;   California;   Colorado;   Connecticut;   Delaware;   Florida;   Georgia;   Hawaii;   Idaho;   Illinois;   Indiana;   Iowa;   Kansas;   Kentucky;   Louisiana;   Maine;   Maryland;   Massachusetts;   Michigan;   Minnesota;   Mississippi;   Missouri;   Montana;   Nebraska;   Nevada;   New Hampshire;   New Jersey;   New Mexico;   New York City;   New York;   North Carolina;   North Dakota;   Ohio;   Oklahoma;   Oregon;   Pennsylvania;   Rhode Island;   South Carolina;   South Dakota;   Tennessee;   Texas;   Utah;   Vermont;   Virginia;   Washington, DC;   Washington;   West Virginia;   Wisconsin;   Wyoming

USA Territories: American Samoa (USA)   Guam (USA)   Puerto Rico (USA)   Virgin Islands (USA)   Northern Mariana Islands (USA)

USA Compact Free Associations: The Federated States of Micronesia (USA)   Marshall Islands (USA)   Republic of Palau (USA)

Canada: Alberta;   British Columbia;   Manitoba;   New Brunswick;   Newfoundland and Labrador;   Northwest Territories;   Nova Scotia;   Nunavut;   Ontario;   Prince Edward Island;   Quebec;   Saskatchewan;   Yukon;


International country outside of the USA, Israel and Canada.

Suggested Grants:

Grants to USA Nonprofits to Address the Climate Crisis and Reduce Inequality

Deadline Ongoing

Grants to USA nonprofit organizations to reduce social inequality and promote solutions to the climate crisis. Eligible programs will address the areas of racial and economic justice, corporate and political accountability; voice, creativity, and culture; and an inclusi

GrantWatch ID#: 123756

Opportunity for California Nonprofits, For-Profits, and Social Enterprises to Participate in...

Deadline 01/28/22

Opportunity for California nonprofit organizations, for-profits, and social enterprises to participate in an initiative that promotes the advancement of the health and wellness of marginalized communities in eligible locations. Participants in the program will take part

GrantWatch ID#: 124605

Grants to Virginia Nonprofits for Public Programs that Promote the Humanities in Local Commu...

Deadline Ongoing

Grants to Virginia nonprofit organizations for programs that promote the humanities in local communities. Certain applicants are required to submit an LOI prior to a full grant application. All applicants are advised to contact Foundation staff prior to submitting a pro

GrantWatch ID#: 125447

Grants to Massachusetts Nonprofits for Community Benefit Programs Primarily to Support Youth

Deadline Ongoing

Grants to Massachusetts nonprofit organizations for community benefit initiatives. A letter of intent must be submitted prior to submitting a full proposal. Priority is given to addressing the needs of low-income youth, children, and their families. The funding source s

GrantWatch ID#: 125830

Grants to USA and Canada Nonprofit Charitable Organizations to Impact Public Policy in a Var...

Deadline Ongoing

Grants to USA and Canada nonprofit charitable organizations to impact public policy in a variety of national and international issues. In previous years, grants have been awarded for general operations and project support to think tanks, national councils, judicial orga

GrantWatch ID#: 125864

Grants to New York and Pennsylvania Families Caring for a Child with Cancer to Offset Treatm...

Deadline Ongoing

Grants to New York and Pennsylvania families living in eligible areas and caring for a child with cancer to offset expenses related to the child's cancer treatments. Funding is intended to cover costs not covered by health insurance, including travel costs, housing, and

GrantWatch ID#: 125904

Grants to USA Nonprofits to Protect Natural Resources

Deadline Ongoing

Grants to USA nonprofit organizations to protect natural resources on land and water in locations around the world. Funding is intended to ensure that activities to acquire metals, gemstones, and corals for design use do not have an adverse impact on the area of origin.

GrantWatch ID#: 126162

Grants to USA Organizations, Tribes, and Tribal Organizations to Provide Services to Childre...

Deadline 01/05/22

Grants to USA and territories community-based organizations, faith-based organizations, tribes, and tribal organizations to provide services to children with special health care needs. Applicants are advised that required registrations may take several weeks to complete

GrantWatch ID#: 126399

Grants to Indiana Nonprofits to Address Community Needs in Eligible Regions

Deadline 03/01/22

Grants to Indiana nonprofit organizations in eligible regions for projects and capital campaigns that address community needs. Applicants requesting support for a capital campaign are asked to contact the funding source prior to submitting an application. Projects are e

GrantWatch ID#: 126506

Grants to Ohio Nonprofits in Eligible Locations to Support Mergers or Acquisitions

Deadline Ongoing

Grants to Ohio nonprofit organizations in eligible locations to support entrance into mergers or acquisitions. Funding is intended to support reorganizations that result in well-maintained or improved services or financial savings. The Foundation encourages transformati

GrantWatch ID#: 126963