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Grants to Canada Researchers at Hospitals and IHEs for Cystic Fibrosis Research

Basic Science Research Grants, Clinical Research Grants and Early Career Investigator Awards


Agency
Foundation

GrantWatch ID#
161561

Funding Source
Cystic Fibrosis Fiborse kystique Canada
Array ( )

Geographic Focus
Canada: Alberta;   British Columbia;   Manitoba;   New Brunswick;   Newfoundland and Labrador;   Northwest Territories;   Nova Scotia;   Nunavut;   Ontario;   Prince Edward Island;   Quebec;   Saskatchewan;   Yukon;

Important Dates
LOI Date: 08/15/23
Deadline: 10/01/23 Save

Grant Description
Grants to Canada researchers affiliated with hospitals and universities to conduct studies related to cystic fibrosis. Applicants are required to submit an LOI prior to a full grant application. Funding is intended to support research projects that enhance the understanding of the disease, advance successful treatment methods, improve the quality of life and health of patients, bridge the gap between research and clinical care, and facilitate research for early-career investigators. Consideration will be given to proposals that have the highest likelihood of positively impacting cystic fibrosis patients.
  • Basic Science Research grants: These grants support innovative basic science research projects that: (i) improve understanding of cystic fibrosis and/or (ii) have a significant impact on the concepts, methods, treatments, and/or technologies applicable to CF. Grant applications submitted to the Basic Science Research Grant stream must focus on basic science research, including molecular, cellular, and animal studies aimed at better understanding the pathology of cystic fibrosis and its complications or the preclinical development of treatments for cystic fibrosis and its complications. 
  • Clinical Research grants: These grants support clinical research projects that: (i) improve the health and quality of life of cystic fibrosis patients and/or (ii) bridge the gap between research and clinical care.
  • Early Career Investigator award: To provide early-career investigators an opportunity to develop outstanding CF research programs and build a team through operating grant support without having to compete against established investigators.

All applications must address Cystic Fibrosis Canada’s Core Principles of funding the best science that has the highest probability of making an impact for CF patients. Research with strong alignment to one or more of the following will be funded:

  1. Cure CF with gene or stem cell therapies
  2. Understand mental health and emotional wellness at different stages
  3. Improve airway infection detection and treatment
  4. Prevent or treat CF-related diabetes
  5. Reduce the treatment burden
  6. Understand health issues for people living with CF aged 50+
  7. Predict and prevent pulmonary exacerbations
  8. Eradicate chronic pseudomonas aeruginosa infections
  9. Reduce hospitalizations by maximizing the therapies that can be done from home
  10. Improve GI pain management
  11. Help people with CF improve and sustain adherence to treatment

Clinical Trials: Cystic Fibrosis Canada recognizes the importance of strong support for clinical trials of new drugs or treatments for cystic fibrosis. In most instances, particularly where new products are involved, funding will emanate from the manufacturer, as a normal component of the drug or product development process. In cases where such funding is not available or appropriate, the organization will entertain applications for limited support. In no instance will Cystic Fibrosis Canada provide financial support to trials which, by their nature, should be assumed by pharmaceutical companies or equipment manufacturers. For further information, see https://www.cysticfibrosis.ca/uploads/Cystic%20Fibrosis%20Canada%20Grants%20and%20Awards%20Guide%202023-2024.pdf#page=25

Travel: Research grants and early career investigator awards include a travel component. The organization encourages investigators to attend CF-related meetings in Canada or elsewhere, when advisable according to public health guidelines, to report on their own research and to remain abreast of significant developments in CF research. Presentation of a paper at a reputable scientific meeting, or attendance at a major symposium or conference related to the grantee's research are considered legitimate uses of travel funds.

Research grants may be allocated, in accordance with the approved budget, to:

  • Personnel salaries/benefits (research assistant(s), technicians, fellows, students, specified other personnel);
  • Principal investigator salary in addition to, but not in lieu of, institutional support. Up to a maximum of 40% of the budget may be requested for salary support;
  • Materials and supplies (expendables, animals, services);
  • Equipment (total not to exceed $10,000, once per term grant);
  • Travel expenses

For additional information on use of funds, see: https://www.cysticfibrosis.ca/uploads/Cystic%20Fibrosis%20Canada%20Grants%20and%20Awards%20Guide%202023-2024.pdf#page=34



Recipient

Additional Eligibility Criteria
- Basic Science Research grant: Applicants must be independent researchers who hold a full-time academic or research appointment relevant to CF at a Canadian university or hospital. Under exceptional circumstances, and at the discretion of the Research Advisory Council, research grant applications from other individuals may be evaluated on a case-by-case basis, with significant emphasis placed on the degree of independence of the applicant, and on the institutional commitments to this individual.
- Clinical Research grant: The applicant must hold an academic or research appointment relevant to CF at a Canadian university or hospital.

There are no limits on the number of co-investigators or collaborators that can be listed. The investigators must have clearly defined roles which are justified. The institution receiving funds indicates where the ultimate responsibility for the grant lies. Generally, the organization funds research which is carried out in Canada, and the principal investigator must be based at a Canadian institution. While Cystic Fibrosis Canada will fund a collaboration from outside of Canada, funds must be directed through a Canadian institution and Canadian investigators intending to collaborate with individuals from outside of Canada should contact Cystic Fibrosis Canada in advance.

- Early Career Investigator award:
At the time of application, candidates must:
- Hold a health professional degree at a doctoral level (e.g. M.D.) or a Ph.D. degree;
- Be within five years (60 months) of, or have a formal documented commitment to, their first full-time academic or research appointment at the time of application;
- Never have held an operating grant from Cystic Fibrosis Canada in the past;
- Have a written commitment from the Dean of Faculty or Research Director
- Be sponsored by a Canadian research institution or medical school;
- Exhibit exceptional potential and demonstrate the ability to initiate and conduct independent research.
For additional eligibility information, see: https://www.cysticfibrosis.ca/uploads/Cystic%20Fibrosis%20Canada%20Grants%20and%20Awards%20Guide%202023-2024.pdf#page=28

Ineligible
Research grants do not provide support for:
- Construction costs;
- Institutional overheads for laboratory facilities;
- Institutional overheads and/or indirect costs of research;
- Costs of clinical care including clinical care for participants of research studies;
- Purchase of equipment in excess of $10,000;
- Severance pay/packages.

Pre-Application Information
Timeline for Basic Science Research Grants, Clinical Research Grants, and Early Career Investigator Awards:
- Letter of Intent to Apply (LOI) deadline: August 15, 2023
- Full Application deadline: October 1, 2023
- Notification: Mid-March

Applications received by the date indicated in the application schedule will be assessed by Cystic Fibrosis Canada's scientific review panel.

Successful grantees must submit all required institutional approvals for experiments involving human participants and/or animals, and/or biohazardous materials by March 31st of the year following that in which the application for a Research grant is submitted.

Investigators are eligible to hold more than one research grant. It is a requirement that the focus of any additional grant application be clearly delineated from any existing ones. The specific aims of an additional grant should represent new approaches to the CF problem, and not an expansion of an existing research program.

It is the organization’s policy that if funds are donated by National Support Groups directly to a Cystic Fibrosis Canada-funded researcher, or to the hospital/host institution organization in the researcher’s name, an equal amount will be deducted from his/her research grant in the following fiscal year.

For Cystic Fibrosis Canada policies, including the support of personnel, see https://www.cysticfibrosis.ca/uploads/Cystic%20Fibrosis%20Canada%20Grants%20and%20Awards%20Guide%202023-2024.pdf#page=10

Estimated Size of Grant
The maximum budget request is $300,000 per year.
Travel Allowance: Maximum per year of the grant: $3000 per individual (included in the budget maximum)

Term of Contract
Grants are awarded for a term of one to three years. They are renewable for one to three years.
Early Career Investigator Awards will be for a one-, two- or three-year period and is non-renewable.

Contact Information
Apply online through proposalCENTRAL: https://proposalcentral.com/

Grants are administered by Cystic Fibrosis Canada's office, to which all correspondence should be directed: research@cysticfibrosis.ca.

Cystic Fibrosis Canada
2323 Yonge St., Suite 800
Toronto, Ontario M4P 2C9
Local: 416-485-9149
Toll free: 1-800-378-2233
info@cysticfibrosis.ca

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