Strategies to Increase Delivery of Guideline-Based Care to Populations with Health Disparities (R01)
Grants to USA Nonprofits, For-Profits, IHEs, and Agencies
for Cardiovascular and Sleep Disorder Research
for Cardiovascular and Sleep Disorder Research
National Institutes of Health (NIH)
10/21/16 5:00 PM Local Time of Applicant Organization
Grants to USA and territories nonprofits, for-profits, government agencies, and IHEs for studies and strategies that improve clinical practice in the field of cardiovascular, lung, blood, and sleep diseases and disorders. LOIs are due by September 21, at least 30 days prior to the final deadline.
Applications that propose strategies with a focus on providers who care for clinical populations with excess burden of cardiovascular, lung, blood, and sleep diseases and disorders, in concert with the health care delivery systems in which they practice, are strongly encouraged. Applications that test systems, infrastructures, and strategies to implement guideline-based care for NHLBI disorders in clinical care settings are also of high programmatic interest.
The purpose of this Funding Opportunity Announcement (FOA) is to encourage the development of innovative, multi-level studies to test systems, infrastructures, and strategies that will accelerate the adoption of guideline-based recommendations into clinical care relevant to HLBS disorders. Proposed strategies that focus on providers who care for clinical populations with excess burden of HLBS diseases and disorders, in concert with the health care delivery systems in which they practice and the patients themselves, are the focus of this initiative.
Systematic reviews of research on guideline implementation strategies find that approaches are most effective when consideration of the unique needs and resources available within specific care settings are taken into account. For this FOA, practice settings could include Federally Qualified Health Centers (FQHC), safety-net facilities, community health centers, public hospitals, and other practice settings treating populations with disparities in HLBS diseases and disorders. Examples of such vulnerable populations include, but are not limited to, medically underserved individuals, racial and ethnic minorities, low-income groups, and rural-dwelling patients.
Health disparities are the result of a complex interplay of patient, provider, and environmental factors. Characteristics such as poor access to health care, low socioeconomic status, insufficient health literacy, inadequate adherence to care, high obesity rates, and increased environmental exposure all play a role. However, the significant health disparities that exist across settings and patient populations are due in part to the lack of uniformity in guideline-based treatment delivery and to lower levels of provider and patient adherence to recommended guidelines. This FOA addresses the providers’ and healthcare system contributions to ongoing disparities.
Specific Areas of Research Interest:
1) Randomized controlled trials testing the impact of multi-level clinical decision support strategies on implementation of cholesterol management guidelines among practitioners providing care in FQHC settings.
2) Trials testing provider acceptability, uptake, adoption, and spread of guidelines with the use of tools that incorporate innovative strategies using a team approach and emerging technologies to enable providers to actively and efficiently engage with patients.
3) Studies testing electronic health record (EHR)-based tools to alert primary care physicians working in low resource clinics of the potential for a patient to have sleep-disordered breathing, and provide detailed feedback regarding guidelines for diagnosis, management and care, including developing ways to effectively assist patients in adhering to recommended treatment.
4) Randomized controlled trials of different tailoring strategies for guideline implementation in health centers that may be at different stages of organizational readiness to change, and that may have diverse strengths, weaknesses, organizational contexts, and patient populations.
5) Randomized controlled trials of multi-level strategies to remediate gaps in clinician adherence to best-practice guidelines for outpatient venous thromboembolism (VTE) risk assessment and care.
Investigations testing strategies for successful guideline-based care among patients with sickle cell disease, thalassemia and other non-malignant blood diseases.
6) Trials testing optimal sequencing (e.g., timing, order, specific combinations) for implementation of two or more guidelines to treat patients with multiple HLBS risk factors or conditions.
7) Studies to identify barriers among providers and healthcare systems to implementing guideline-based lifestyle treatment for obesity, and strategies to overcome these barriers.
The maximum project period is five years.
- City or township governments
- County governments
- For profit organizations other than small businesses
- Independent school districts
- Indian housing authorities
- Native American tribal governments (Federally recognized)
- Native American tribal organizations (other than Federally funded tribal governments)
- Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education
- Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education
- Private institutions of higher education
- Public and State controlled institutions of higher education
- Public housing authorities
- See RFP and/or Grant Guidelines for full eligibility
- Small businesses
- Special district governments
- State governments
Higher Education Institutions:
-Public/State Controlled Institutions of Higher Education
-Private Institutions of Higher Education
The following types of Higher Education Institutions are always encouraged to apply for NIH support as Public or Private Institutions of Higher Education:
-Historically Black Colleges and Universities (HBCUs)
-Tribally Controlled Colleges and Universities (TCCUs)
-Alaska Native and Native Hawaiian Serving Institutions
-Asian American Native American Pacific Islander Serving Institutions (AANAPISIs)
Nonprofits Other Than Institutions of Higher Education:
-Nonprofits with 501(c)(3) IRS Status (Other than Institutions of Higher Education)
-Nonprofits without 501(c)(3) IRS Status (Other than Institutions of Higher Education)
-For-Profit Organizations (Other than Small Businesses)
-City or Township Governments
-Special District Governments
-Indian/Native American Tribal Governments (Federally Recognized)
-Indian/Native American Tribal Governments (Other than Federally Recognized)
-Eligible Agencies of the Federal Government
-U.S. Territory or Possession
-Independent School Districts
-Public Housing Authorities/Indian Housing Authorities
-Native American Tribal Organizations (other than Federally recognized tribal governments)
-Faith-based or Community-based Organizations
-Non-domestic (non-U.S.) Entities (Foreign Institutions) are not eligible to apply.
-Non-domestic (non-U.S.) components of U.S. Organizations are not eligible to apply.
-Foreign components, as defined in the NIH Grants Policy Statement, are not allowed.
Letters of Intent are due 30 days prior to the application due date.
Upcoming application deadlines are:
-October 21, 2016
-June 21, 2017
-October 20, 2017
-June 21, 2018
All types of non-AIDS applications allowed for this funding opportunity announcement are due on these dates.
Applicants are encouraged to apply early to allow adequate time to make any corrections to errors found in the application during the submission process by the due date.
Application instructions may be found here: http://grants.nih.gov/grants/how-to-apply-application-guide.htm
There are several options to submit your application to the agency through Grants.gov. You can use the ASSIST system to prepare, submit and track your application online. You can download an application package from Grants.gov, complete the forms offline, submit the completed forms to Grants.gov and track your application in eRA Commons. Or, you can use other institutional system-to-system solutions to prepare and submit your application to Grants.gov and track your application in eRA Commons.
Applicant organizations must have completed the following registrations prior to applying:
-Dun and Bradstreet Universal Numbering System (DUNS) - All registrations require that applicants be issued a DUNS number. After obtaining a DUNS number, applicants can begin both SAM and eRA Commons registrations. The same DUNS number must be used for all registrations, as well as on the grant application.
-System for Award Management (SAM) (formerly CCR) – Applicants must complete and maintain an active registration, which requires renewal at least annually. The renewal process may require as much time as the initial registration. SAM registration includes the assignment of a Commercial and Government Entity (CAGE) Code for domestic organizations which have not already been assigned a CAGE Code.
-NATO Commercial and Government Entity (NCAGE) Code – Foreign organizations must obtain an NCAGE code (in lieu of a CAGE code) in order to register in SAM.
-eRA Commons - Applicants must have an active DUNS number and SAM registration in order to complete the eRA Commons registration. Organizations can register with the eRA Commons as they are working through their SAM or Grants.gov registration. eRA Commons requires organizations to identify at least one Signing Official (SO) and at least one Program Director/Principal Investigator (PD/PI) account in order to submit an application.
-Grants.gov – Applicants must have an active DUNS number and SAM registration in order to complete the Grants.gov registration.
Registration can take six weeks or more, so applicants should begin the registration process as soon as possible. The NIH Policy on Late Submission of Grant Applications states that failure to complete registrations in advance of a due date is not a valid reason for a late submission.
View this opportunity on Grants.gov: http://www.grants.gov/web/grants/search-grants.html?keywords=PAR-15-279
Before starting your grant application, please review the funding source's website listed below for updates/changes/addendums/conferences/LOIs.
Apply online using ASSIST: http://grants.nih.gov/grants/guide/ApplyButtonSplash.cfm
Application Submission Contacts:
eRA Service Desk:
Online Help: http://grants.nih.gov/support/index.html
301-402-7469 / 866-504-9552 (Toll Free)
Grants.gov Customer Support
GrantsInfo@nih.gov (preferred method of contact)
Catherine M. Stoney, PhD
National Heart, Lung, and Blood Institute (NHLBI)
Financial/Grants Management Contact:
National Heart, Lung, and Blood Institute (NHLBI)
93.233 -- National Center on Sleep Disorders Research / 93.837 -- Cardiovascular Diseases Research / 93.838 -- Lung Diseases Research / 93.839 -- Blood Diseases and Resources Research
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