Foundation / Corporation
Harrington Discovery Institute and Foundation Fighting Blindness - The Harrington Project for Discovery and Development
01/19/18 Midnight EST
Awards to recognize USA and Canada individual scientists and physicians whose innovative research has the potential to advance medical therapies for those suffering from retinal degenerative diseases. Letters of Intent are due by October 25. This funding initiative is focused on accelerating the translation of research findings in inherited retinal degenerative diseases, with the ultimate goal of developing new therapies to prevent, treat, or cure blindness.
Funding will be provided for translational drug development and cell therapy, and for non-financial project support to help bridge the gap between laboratory-based research and the clinic.
Multi-Level Support for Award Recipients Includes:
- Funding totaling up to $900,000 over three years based on progress made towards milestones
- Committed drug development and project management support through the Harrington Discovery Institute’s Innovation Support Center team of pharmaceutical experts for the 3 year term
- Dedicated pharma team provided for each scholar
- Business and commercialization assessment
- Clinical development strategy
- Regulatory guidance
- Intellectual property review and strategy
- Access to contract research organizations/service providers Award Criteria:
Areas of interest include:
- Inherited retinal degenerations such as retinitis pigmentosa, Leber’s congenital amaurosis, cone dystrophies, and juvenile macular dystrophies like Stargardt or Best disease, choroideremia, and retinoschisis. In general, inherited retinal degenerative diseases that impact photoreceptors or RPE primarily.
- Targeting of pathways and processes that might affect retinal dystrophies and vision, with the ultimate goal of advancing the translation of research programs into therapies for the prevention and treatment of these diseases.
- Therapies based on novel targets
- Treatment strategies that are not gene specific, but may be broadly applicable across many patients such as therapies that may be effective for later stages of disease
- Therapies that address juvenile macular degeneration
- Regenerative medicine therapies that focus on stem cells differentiated into photoreceptor cells or precursors
- Therapies developing gene delivery vectors or gene modifying strategies that can be used as a general platform to target specific retinal cell types, deliver/correct genes with large coding regions, specifically target outer retinal cells or impact cells across the entire retinal area
GrantWatch ID#: 182102
There is an average of three awards per year.
- The competition is open to investigators at accredited academic medical centers, research institutions, and universities in the USA and Canada. Applications from institutions outside these two countries are not accepted.
- Applicants must have a PhD or MD degree (or equivalent) and demonstrate exceptional promise.
- Multidisciplinary investigators outside the field of retinal disease developing a therapeutic strategy with a potential to benefit inherited retinal degenerative diseases are particularly encouraged to apply.
- Of particular interest is the targeting of pathways and processes that might affect inherited retinal dystrophies and vision, with the ultimate goal of advancing the translation of research programs into therapies for the prevention and treatment of these diseases. In most cases, device development is not supported.
August 1, 2017: Call for Letters of Intent Opens
October 25, 2017: Letter of Intent* Deadline (midnight EST)
January 19, 2018: Full Application Deadline for those invited (midnight EST)
*Click on the link in the Supporting Documents section below to download the Letter of Intent guidelines.
Click here for more information: http://www.uhhospitals.org/services/harrington-discovery-institute/funding-and-programs/gund-harrington-scholar-program
Click here for information on how to apply: http://www.uhhospitals.org/services/harrington-discovery-institute/funding-and-programs/gund-harrington-scholar-program/how-to-apply
Before starting your grant application, please review the funding source's website listed below for updates/changes/addendums/conferences/LOIs.
Click here to apply online: https://harringtondiscovery.smartsimple.com/s_Login.jsp
Mailing Address: 10900 Euclid Avenue, Mail Stop 7294 Cleveland, OH 44106
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