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Pervasive Needs Grants

Grants to USA Nonprofits for Projects to Benefit
Individuals Affected by Neurodegenerative Diseases

Agency Type:

Foundation / Corporation

Funding Source:

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Adira Foundation

LOI Date:


Deadline Date:



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Grants to USA and territories nonprofit organizations for programs that improve the lives of individuals with neurodegenerative diseases (ND) and their caregivers. Applicants must submit a letter of intent prior to submitting a full proposal. Funding is intended for projects that provide immediate benefit to people living with ND and their caregivers while creating, testing, or disseminating a best practice for ND care with the intent to continuously improve and enhance the ability of systems to impact quality of life in ND.

Adira Foundation was created to counter the unforeseen consequences of siloed, disease-specific approaches that can lead to gaps in seeing and addressing shared systemic barriers, health inequities and day-to-day needs of patients and caregivers across complex health issues. Adira’s inaugural focus is on neurodegenerative diseases (ND) including ALS (amyotrophic lateral sclerosis), Alzheimer’s and related dementias, Huntington’s disease (HD), multiple sclerosis (MS), and Parkinson’s disease.


  1. Simplifying clinical research: Programs that provide education, navigation, or direct support services to people living with neurodegenerative diseases and caregivers to facilitate the removal of participation barriers in clinical trials and research.
  2. Preparing for future threats to livelihood: Programs that support education, navigation, and skill-building activities that provide opportunity for people living with neurodegenerative diseases and caregivers to prepare and implement a planned, phased approach to their disease journey.
  3. Thriving again in common pursuits: Programs that support inclusive social and recreational activities, providing opportunity for people living with neurodegenerative diseases and caregivers to easily access and enjoy community-based spaces and resources.

Priority will be given to projects that include these elements:

  • Aggregating - Project serves people from two or more of the five neurodegenerative diseases.
  • Convening - Project includes convening activities seeking the collective input of multiple people living with one of the five NDs, caregivers, or related stakeholders to improve the design, delivery, or measurement of the project. Bringing together individuals with different perspectives, such as people living with NDs and caregivers, is a plus.
  • Health Equity - Project includes activities that serve groups historically experiencing less power and privilege by addressing an evidence-based health disparity or health inequity. Additional consideration will be given to projects that address a specific health inequity.

GrantWatch ID#:

GrantWatch ID#: 192967

Estimated Total Program Funding:


Number of Grants:

Adira anticipates funding at least 3-5 projects.

Estimated Size of Grant:

Total grant target: $500,000 - Adira is seeding the first $250,000, and pursuing cofinancing of $250,000 to match.

The average grant amount is $60,000.

Term of Contract:

Adira seeks proposals for a 12-month project period. The project period is February 2022 - February 2023.

Additional Eligibility Criteria:

Applicants must meet the following criteria:
- 501(c)(3) nonprofit in good standing.
- Currently serving people with ALS (amyotrophic lateral sclerosis), Alzheimer’s disease and related dementias, Huntington’s disease, multiple sclerosis, or Parkinson’s disease and/or their caregivers.

Smaller, community-based organizations are encouraged to apply.

Individuals and private corporations are not eligible to apply.

Pre-Application Information:

Letters of Intent are due by 5 p.m. ET on Oct. 18.

Key Dates
- LOI Submission Deadline: October 18
- Notification of Advancement: November 12
- Proposal Deadline: December 6

For more information, see

Contact Information:

Before starting your grant application, please review the funding source's website listed below for updates/changes/addendums/conferences/LOIs.

Submit LOI to Lauren Ruiz at

URL for Full Text (RFP):

Geographic Focus:

USA: Alabama;   Alaska;   Arizona;   Arkansas;   California;   Colorado;   Connecticut;   Delaware;   Florida;   Georgia;   Hawaii;   Idaho;   Illinois;   Indiana;   Iowa;   Kansas;   Kentucky;   Louisiana;   Maine;   Maryland;   Massachusetts;   Michigan;   Minnesota;   Mississippi;   Missouri;   Montana;   Nebraska;   Nevada;   New Hampshire;   New Jersey;   New Mexico;   New York City;   New York;   North Carolina;   North Dakota;   Ohio;   Oklahoma;   Oregon;   Pennsylvania;   Rhode Island;   South Carolina;   South Dakota;   Tennessee;   Texas;   Utah;   Vermont;   Virginia;   Washington, DC;   Washington;   West Virginia;   Wisconsin;   Wyoming

USA Territories: American Samoa (USA)   Guam (USA)   Puerto Rico (USA)   Virgin Islands (USA)   Northern Mariana Islands (USA)

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