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Grants to USA Health Centers in Multiple States
for Services to Prevent the Spread of HIV

FY 2022 Ending the HIV Epidemic (EHE)– Primary Care HIV Prevention (PCHP) Funding

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Funding Source:

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US Department of Health and Human Services (DHHS) - Health Resources and Services Administration (HRSA)

Deadline Date:

12/14/21 11:59 PM ET - deadline; 01/18/22 5:00 PM ET - HRSA EHBs deadline.


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Grants to USA health centers in eligible regions for services that prevent the spread of HIV. Applicants are advised that required registrations may take up to several weeks to complete. Eligible programs must implement activities in the following focus areas: testing, prescription of PrEP, workforce development, and outreach. Eligible applicants are those listed on the list of eligible health centers.

This notice announces the opportunity to apply for FY 2022 Ending the HIV Epidemic – Primary Care HIV Prevention (PCHP) funding. PCHP funding will expand HIV prevention services that decrease the risk of HIV transmission in underserved communities in support of Ending the HIV Epidemic in the U.S. This FY 2022 funding opportunity will make available HIV prevention investments to Health Center Program operational (H80) award recipients located in Ending the HIV Epidemic in the U.S. geographic locations that did not receive FY 2020 or FY 2021 PCHP funding.

Announced in 2019, Ending the HIV Epidemic in the U.S. (EHE) is a Department of Health and Human Services (HHS) initiative to reduce the number of new HIV infections by 75 percent by 2025, and by at least 90 percent by 2030. Activities in the first 5 years of the initiative focus on identified HIV hot spots (targeted geographic locations3): 48 counties; Washington, D.C.; San Juan, Puerto Rico; and seven states that have a substantial rural HIV burden. The initiative includes four strategies:

  • Diagnose all people with HIV as early as possible after transmission.
  • Treat people with HIV rapidly and effectively to reach sustained viral suppression.
  • Prevent new HIV transmission by using proven interventions, including preexposure prophylaxis (PrEP) and syringe services programs (SSPs).
  • Respond quickly to potential HIV outbreaks to get needed prevention and treatment services to people who need them.

You must propose to use PCHP funds to achieve three objectives:

  1. Increase the number of patients counseled and tested for HIV.
  2. Increase the number of patients prescribed PrEP.
  3. Increase the number of patients linked to HIV care and treatment within 30 days of diagnosis.

PCHP funds may support HIV prevention activities throughout your service area with a focus on the EHE targeted geographic location. To maximize PrEP access, your proposed project must make reasonable efforts to incorporate the use of available medication assistance and donation programs, including Ready, Set, PrEP, before using PCHP funds to support access to PrEP for health center patients.

GrantWatch ID#:

GrantWatch ID#: 199891

Estimated Total Program Funding:


Number of Grants:


Estimated Size of Grant:

Estimated Award Amount: $325,000 per year, subject to availability of funds

Term of Contract:

Period of Performance: 2 years, beginning August 1, 2022

Additional Eligibility Criteria:

Organizations eligible for PCHP funding:
• Are Health Center Program operational (H80) grant award recipients under sections 330(e), (g), (h), and/or (i),
• Have at least one operational service delivery site at a fixed address in one of the targeted geographic locations, and
• Did not receive an FY 2020 or FY 2021 PCHP award.

See the PCHP technical assistance webpage for a list of eligible health centers:

Funds under this notice may not be used for the following costs:
• Costs already supported by the H80 operational grant;
• Costs already supported by current supplemental funding (e.g., H8F);
• Purchase or upgrade of an EHR that is not certified by the Office of the National Coordinator for Health Information Technology;
• New construction activities, including additions or expansions;
• Minor A/R projects;
• Installation of trailers and pre-fabricated modular units;
• Facility or land purchases;
• Purchase of vehicles to transport patients or health center personnel;
• Needles and syringes for illegal drug injection; or
• Devices solely used for illegal drug injection (e.g., cookers).34

Pre-Application Information:

Due Date for Applications – December 14, 2021 (11:59 p.m. ET)
Due Date for Supplemental Information – HRSA Electronic Handbooks (EHBs): January 18, 2022 (5 p.m. ET)

HRSA suggests submitting applications to at least 3 calendar days before the deadlines to allow for any unforeseen circumstances.

Ensure your SAM and registrations and passwords are current immediately. HRSA will not approve deadline extensions for lack of registration. Registration in all systems, including,, and EHBs
may take up to one month to complete.

HRSA requires you to apply electronically through and EHBs. You must use a two-phase submission process associated with this NOFO and follow the directions provided at and in EHBs.
• Phase 1 – – Required information must be submitted and validated via with a due date of December 14, 2021 at 11:59 p.m. ET; and
• Phase 2 – EHBs – Supplemental information must be submitted via EHBs with a due date of January 18, 2022 at 5 p.m. ET.

Only applicants who successfully submit the workspace application package associated with this NOFO in (Phase 1) by the due date may submit the additional required information in EHBs (Phase 2).

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For a list of relevant application documents, see the Package tab (click Preview) on the link listed above.

Watch the presentation for applicants recording:

Contact Information:

Before starting your grant application, please review the funding source's website listed below for updates/changes/addendums/conferences/LOIs.

You may request additional information and/or technical assistance regarding business, administrative, or fiscal issues including budget development related to this NOFO by contacting:
Doris Layne-Sheffield
Grants Management Specialists
Division of Grants Management Operations
Office of Financial Assistance Management (OFAM)
Health Resources and Services Administration
5600 Fishers Lane, Room 10W61A
Rockville, MD 20857
Telephone: (301) 945-9881

You may request additional information and/or technical assistance related to this
NOFO’s programmatic requirements by contacting:
Rebecca Levine
Public Health Analyst
Office of Policy and Program Development
Bureau of Primary Health Care (BPHC)
Health Resources and Services Administration
5600 Fishers Lane, Room 16N46C
Rockville, MD 20857
Telephone: (301) 594-4300

For assistance with submitting the application in, contact 24 hours a day, 7 days a week, excluding federal holidays at: Contact Center
Telephone: 1-800-518-4726, (International Callers, dial 606-545-5035)
Self-Service Knowledge Base:

For assistance with submitting the remaining information in EHBs, contact Health Center Program Support, Monday-Friday, 7:00 a.m. to 8:00 p.m. ET, excluding federal holidays at:
Health Center Program Support
Telephone: 1-877-464-4772

Grant Coverage Areas:

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URL for Full Text (RFP):

Geographic Focus:

USA: Alabama;   Arizona;   Arkansas;   California;   Florida;   Georgia;   Illinois;   Indiana;   Kansas;   Louisiana;   Maryland;   Massachusetts;   Michigan;   Mississippi;   Missouri;   Nevada;   New Jersey;   New York City;   New York;   North Carolina;   Ohio;   Oklahoma;   Pennsylvania;   South Carolina;   Tennessee;   Texas;   Washington, DC;   Washington

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