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Contracts for Services to USA Nonprofits, For-Profits, IHEs, and Agencies for Health-Related Research

Broad Pragmatic Studies Funding


GrantWatch ID#

Funding Source
Patient-Centered Outcomes Research Institute (PCORI)
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Geographic Focus

Important Dates
LOI Date: 05/31/23
Deadline: 08/29/23 5:00 PM ET Save

Grant Description
Contracts for services to USA nonprofit and for-profit organizations, IHEs, and government agencies for research projects on a wide range of health-related topics. Applicants must submit a letter of intent prior to submitting a full application. Funding is intended for research addressing health equity, health communication, and increasing evidence for existing interventions and emerging innovations in health.
This funding opportunity seeks applications that address PCORI’s National Priorities for Health. To be considered responsive, applications must describe research that compares at least two alternative approaches to achieve one or more of the National Priorities for Health:
  • Increase Evidence for Existing Interventions and Emerging Innovations in Health
  • Accelerate Progress Toward an Integrated Learning Health System
  • Achieve Health Equity
  • Advance the Science of Dissemination, Implementation, and Health Communication

This funding opportunity contains three categories for funding, which are applicable to the four National Priorities for Health:

  • Category 1: Less than or equal to $5 million in direct costs
  • Category 2: Greater than $5 million in direct costs and up to $10 million in direct costs
  • Category 3: PCORnet® Studies up to $10 million in direct costs

For additional information about the research areas, see:

Topic Themes and Key Topics:


Additional Eligibility Criteria
In general, applications for the conduct of research and management of funding may be submitted by appropriate academic research, private sector research, or study-conducting entities. This may include, among others, agencies and instrumentalities of the Federal Government, nonprofit and for-profit research organizations, and colleges and universities.

Foreign Organizations and Nondomestic Components of U.S. Organizations must provide a thorough and thoughtful justification for the research's ability to benefit the US healthcare system and that the engagement plans include US patients and stakeholders, and are relevant to US healthcare system.

Individuals are not permitted to apply.

Funding Restrictions:

Pre-Application Information
Key Dates:
- Online System Opens: May 2, 2023
- Applicant Town Hall: May 17, 2023, 11:30 am ET
- Overview of PCORnet Workshop: May 18, 2023, 2 pm ET
- Deep dive into PCORnet Workshop: July 13, 2023, 1pm ET
- Letter of Intent (LOI) Deadline: May 31, 2023, by 5 pm (ET)
- LOI Status Notification: June 27, 2023
- Application Deadline: August 29, 2023, by 5 pm (ET)
- Merit Review: November 2023
- Awards Announced: March 2024
- Earliest Project Start Date: July 2024

Applying for funding through this PFA is a two-stage process. An LOI must be submitted, and an applicant must be invited to submit an application. Only applicants whose LOIs are deemed most responsive to this PFA will be invited to submit a full application.

Recorded Applicant Town Hall:

Broad Pragmatic Studies FAQs:

Applicant FAQs:

Tops for Preparing a Responsive LOI:

Additional Funding Information

Estimated Total Program Funding:


Estimated Size of Grant
Total Direct Costs:
• Category 1: Less than or equal to $5 million direct costs
• Category 2: Greater than $5 million; up to $10 million direct costs
• Category 3: PCORnet® Studies up to $10 million direct costs

Term of Contract
Earliest Start Date: July 2024

Maximum Project Period: Up to 5 years for all Categories

Contact Information
Submit LOI and application online:

Programmatic Inquires: or online (

Administrative, Financial, or Technical Inquiries:

Patient-Centered Outcomes Research Institute
1333 New Hampshire Avenue NW, Suite 1200
Washington, DC 20036
Phone: (202) 827-7700
Fax: (202) 355-9558

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