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Grants to USA Investigators for Healthcare-Related Research


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Greater Value Portfolio Grant

Donaghue Foundation

Grant Provider's 990

Agency: Foundation

GrantWatch ID #155209

Grant Description

Grants to USA investigators at tax-exempt research institutions for research related to healthcare. Applicants must submit an LOI prior to submitting a full application. Under this grant program, researchers will partner with healthcare service providers to test promising strategies that organizations can readily use to improve the value of the healthcare they provide to patients and communities.

In 2022, the Donaghue Foundation’s Greater Value Portfolio grant program will fund research projects for the purpose of advancing promising approaches to achieve a higher value healthcare system. The goal of this program is to test approaches and tools that organizations can readily use to improve the value of the healthcare they provide to their patients and communities.

Investigators conducting research to develop actionable solutions to one or more of these symptoms of low-value healthcare are encouraged to apply to the Greater Value Portfolio program:

  • High and rising healthcare costs
  • Unwarranted variation in prices
  • Racial and ethnic disparities in access, prices, and outcomes
  • Unaffordable cost of care burden on patients and families
  • Unacceptable variation in quality
  • Lack of transparency in both price and outcomes

Investigators conducting research to develop actionable solutions to one or more of these symptoms of low-value healthcare are encouraged to apply to the Greater Value Portfolio program.

Eligible topics include studies that focus on improving value through promising strategies using one or more of these approaches:

  • Test models of care, coverage, or system change that  seek to improve value by addressing one or more of the symptoms of low value
  • Reduce treatments, tests, and screenings for patients for whom the potential harms (including financial harm) outweigh potential benefits
  • Provide tools to help consumers make decisions about their healthcare based on value, including the cost of care to patients, in addition to other patient-centered factors
  • Promote conversations between patients and their clinicians and care teams about preferences and trade-offs related to alternative treatment options and /or out of pocket cost burden to patients and families
  • Test interventions geared to increasing equity through the provision of higher value healthcare

For eligible uses of funding, see

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  • Others (see text field entitled "Additional Eligibility Criteria" for clarification)

Additional Eligibility Criteria:

This program is open to Ph.D. (or equivalent) investigators at tax-exempt research institutions in the United States. In order to receive an award, the applicant must partner with an organization that delivers healthcare services or be a researcher based in a research unit embedded in a healthcare organization. Partner organizations cannot be the applicant organization.

The applicant organization must be 501(c)3 research institutions. Donaghue requires that the applicant organization has adequate infrastructure to assure:
- Ethical conduct of research, protection of research participants, and appropriate data protections
- Financial monitoring of grant awards and administering any related subcontracts
- Resources to assist the principal investigator with dissemination activities

Current Donaghue grantees cannot apply for a GVP award if their current grant term would overlap with the time the GVP grant would begin.

Topics that are not considered relevant to the purpose of the program are efficacy trials, basic research, or research using animal models.

For ineligible uses of funding, see

Pre-Application Information:

Timeline for Application Process
- March 8, 2022: Letters of intent due by 5:00 pm EST
- June 16, 2022: Applications due
- December 1, 2022: Grant term begins

The application process will have two phases. Phase 1 is a letter of intent. Following a review of all letters of intent, the Foundation will begin Phase 2 by inviting some applicants to complete a more substantial application.

Applicants may submit more than one LOI.

A partial payment of the award will be made at the start of the first year, and the balance of the funding will be made at the start of the second year upon receipt of an accepted annual report.

Additional Funding Information:

Number of Grants:

In 2022, the Foundation expects to make four awards.

Estimated Size of Grant:

Maximum amount of $400,000 per award (plus a 10% indirect)

Term of Contract:

The duration of the award is two years. No-cost extensions may be requested.

Contact Information:

Submit questions and Letters of Intent, and applications to Shamira Chappell, Program Coordinator, at

The Patrick and Catherine Weldon Donaghue Medical Research Foundation
18 North Main Street
West Hartford, Connecticut 06107-1998

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