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Grants to USA, Canada, and International Teams of
Scientists for Research Projects in the Life Sciences

Human Frontier Science Program (HFSP) Research Grant Program - Early Research and Program Grants

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Foundation / Corporation

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Human Frontier Science Program Organization (HFSPO)

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Grants to USA, Canada, and International teams of scientists for research projects in the life sciences. Funding is intended to support research projects that are international, collaborative, interdisciplinary, and cutting-edge. HFSPO attaches highest importance to novelty, scientific merit, internationality, and interdisciplinarity.

The aim of the Program is to promote, through international cooperation, basic research focused on the elucidation of the sophisticated and complex mechanisms of living organisms, for the benefit of all humankind. It aims to complement, not duplicate, the frontier life science programs of the countries that financially support HFSPO.

Research topics may include biological functions at all levels of analysis: for example, studies on genes and individual molecules, intracellular networks, intercellular associations in tissues and organs, and networks underlying the complex functions of entire organisms, populations, or ecosystems.

Two kinds of research grants are available, the Research Grants - Early Career (previously called Young Investigator Grants) and Research Grants - Program.

Resarch Grants - Program

Research Grants - Program are meant to allow teams of independent researchers to develop new lines of research through a new collaboration. Priority will be given to new, innovative research projects and teams including members from outside the life sciences. Applicants for RG-Program are encouraged to include independent investigators early in their careers as members of their team.

Research Grants - Early Career

These awards have formerly been known as Young Investigator’s Grants (see “Recent changes” on page one of the guidelines in Supporting Documents, below, for explanation). They are meant to encourage outstanding scientists in the initial period of their independent careers, to formulate innovative and promising research projects. Typically, “Early Career” team members will have completed one or two periods of postdoctoral training and be appointed to independent staff positions that allow them to initiate and direct their own independent lines of research.

GrantWatch ID#:

GrantWatch ID#: 187725

Estimated Size of Grant:

- The current mode of funding is as follows but may be subject to revision to take into account HFSPO’s budget: $265,000 for a team of 2; $365,000 for a team of 3; $465,000 for a team of 4 or more.
- Two members from the same country should constitute an interdisciplinary collaboration. They will be awarded an amount equivalent to 1.5 team members (currently $315,000 for a team of ‘2.5’ and $415,000 for ‘3.5’ team members).
- In the case of a two-member team with one member in a for-profit institution, the total annual award will be reduced to $130,000. In other cases, the for-profit member will not be included when calculating the amount of the award.

Term of Contract:

Each grant is awarded for a period of three years.

Additional Eligibility Criteria:

Scientists applying for a HFSP research grant must be organized as an international research team (with emphasis on intercontinental collaborations). Applications from individual researchers are not eligible. The HFSP research team may include 2 to 4 (rarely 5) members, whereby one member of the team is designated as the Principal Applicant and the others as Co-Applicants.

All team members must have a research doctoral degree (PhD, MD or equivalent) and must lead a research group (however small). All team members must be in the position to determine the course of the HFSP-funded project and have freedom to administer the awarded grant. “Post-docs” are not eligible.

HFSPO promotes new interdisciplinary collaborations across the world. Therefore, team members are expected to work in different disciplines and have their labs in different countries.

HFSPO promotes new research collaborations. Therefore, the team members should not have collaborated before, they will normally not have published original research together and must propose a project significantly different from their ongoing research.

The Principal Applicant must be working at a non-profit academic institution. The team may include members from for-profit organizations if their expertise is necessary for the project. However, such team members may not receive any funds and will not be considered in calculating the amount of award.

For more details on eligibility, see the following link:

For a list of ineligible projects and expenses, see the following link:

Pre-Application Information:

- Compulsory initiation of a Letter of Intent by obtaining a LIXXXX/2022 reference number by March 18th, 2021
- Submission of a Letter of Intent: March 30th, 2021
- Submission of Full Applications: mid-September 2021, on invitation only

Projects will be pre-screened upon reception by a small scientific committee (three HFSP Scientific Directors and two members of the Review Committee) for the eligibility of the applicants and for concordance with the scientific scope. Any project that does not meet the requirements will not be sent for review, and the Principal Applicant will be informed as soon as possible.

In a second step, a Selection Committee will take the decision which applicants are invited to submit a full application. Applicants will be notified early July 2021 whether they are invited to submit a full application, with a deadline mid-September 2021.


Contact Information:

Before starting your grant application, please review the funding source's website listed below for updates/changes/addendums/conferences/LOIs.

Apply online:

12, quai Saint-Jean
Tel: +33 3 88 21 51 ext. 26 or 37

URL for Full Text (RFP):

Geographic Focus:

USA: Alabama;   Alaska;   Arizona;   Arkansas;   California;   Colorado;   Connecticut;   Delaware;   Florida;   Georgia;   Hawaii;   Idaho;   Illinois;   Indiana;   Iowa;   Kansas;   Kentucky;   Louisiana;   Maine;   Maryland;   Massachusetts;   Michigan;   Minnesota;   Mississippi;   Missouri;   Montana;   Nebraska;   Nevada;   New Hampshire;   New Jersey;   New Mexico;   New York City;   New York;   North Carolina;   North Dakota;   Ohio;   Oklahoma;   Oregon;   Pennsylvania;   Rhode Island;   South Carolina;   South Dakota;   Tennessee;   Texas;   Utah;   Vermont;   Virginia;   Washington, DC;   Washington;   West Virginia;   Wisconsin;   Wyoming

USA Compact Free Associations: The Federated States of Micronesia (USA)   Marshall Islands (USA)   Republic of Palau (USA)

Canada: Alberta;   British Columbia;   Manitoba;   New Brunswick;   Newfoundland and Labrador;   Northwest Territories;   Nova Scotia;   Nunavut;   Ontario;   Prince Edward Island;   Quebec;   Saskatchewan;   Yukon;


International country outside of the USA, Israel and Canada.

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