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Grants to USA, Canada, and International Investigators for Research
to Improve the Quality of Life for Cancer Patients and Survivors


Agency Type:

Foundation / Corporation

Funding Source:

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Health and Environmental Sciences Institute (HESI)

LOI Date:


Deadline Date:

03/14/22 5:00 PM EST


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Grants of up to $50,000 to USA, Canada, and International investigators holding an M.D., Ph.D., D.V.M., or equivalent degree and affiliated with a research institution to improve the quality of life for cancer patients and survivors. Applicants are required to submit an LOI prior to submitting a full proposal.

THRIVE offers funding for basic science, clinical, and translational research that enhances the ability to predict when and how adverse effects may occur in patients who have received cancer treatment and supports the development of approaches to avoid or lessen these effects. By providing researchers with both seed funding and access to critical networks, THRIVE will enhance the visibility of the patient need, the value of the research, and the reasons that larger funding entities might elect to incorporate these research streams into future funding priorities.

The THRIVE grant program is designed to provide seed funding to investigators for the testing of initial hypotheses and collecting of preliminary data to help secure long-term funding by the National Institutes of Health and/or other major granting institutions.

THRIVE gives preference to those innovative research projects that engage both non-clinical and clinical scientists in the research project design and/or implementation. THRIVE believes that research at the translational boundary can make significant impact on the science and patients. This research will advance:

  • Fundamental understanding of cancer drug or therapy-related toxicity;
  • Ability to identify and translate critical biomarkers of toxicity;
  • Models (in vivo, in vitro, in silico) of pediatric or adult drug exposure that predict early or impending toxicities;
  • Understanding of the role of protective co-therapies or modified exposure protocols on the onset of therapy-induced damage; and
  • Identification of novel protective therapies or dosing-strategies

GrantWatch ID#:

GrantWatch ID#: 193614

Estimated Size of Grant:

- Funding is available in the range of US$20,000 to US$50,000.
- If funding permits, awardees may also receive additional travel funds to support their participation in the HESI THRIVE annual research meeting and networking event.

Term of Contract:

Awards will provide for up to 24 months of total direct costs only. The funding period will initiate May 2, 2022.

Additional Eligibility Criteria:

Principal investigator(s) must hold an M.D., Ph.D., D.V.M., or equivalent degree. Candidates for these degrees along with their Principal Investigator may apply. All candidates must have an accredited faculty, medical institution, or other research institute appointment and have the ability to conduct independent research with publications in established peer-reviewed medical and scientific journals. This funding opportunity is open internationally. Awardees must be willing to participate in the annual HESI THRIVE research forum – an opportunity to share results and build a network of experts.

THRIVE does not cover institutional construction or renovation, purchase of capital equipment other than what is needed for the proposed research, office equipment or furniture, equipment service contracts, non-study related travel, tuition fees, journal subscriptions, dues or memberships, and publication fees.

Pre-Application Information:

- October 18, 2021: Open call for letters of intent
- January 10, 2022: Letters of intent submission date
- February 14, 2022: Notifications sent to those who are invited to submit a full proposal
- March 14, 2022: Full proposals for selected LOIs due
- April 29, 2022: Award selection and notification
- May 2, 2022: Award period launched

THRIVE requires a letter of intent in advance of the grant application. Only investigators who have submitted a letter of intent and have been invited to submit a formal grant application will be considered for THRIVE funding.

No extensions of the deadline can be made. Once submitted, a confirmation email will be sent by THRIVE.

Upon receipt of a signed notification and agreement to THRIVE award terms (including IRB or IACUC approval) THRIVE will disburse 75% of the funds. The remaining 25% of the award is provided upon completion of the study milestones. Exceptions may be made.

Program Overview:

Contact Information:

Before starting your grant application, please review the funding source's website listed below for updates/changes/addendums/conferences/LOIs.

All letters of intent and grant submissions are to be sent to:

For questions, contact the above email address.

URL for Full Text (RFP):

Geographic Focus:

USA: Alabama;   Alaska;   Arizona;   Arkansas;   California;   Colorado;   Connecticut;   Delaware;   Florida;   Georgia;   Hawaii;   Idaho;   Illinois;   Indiana;   Iowa;   Kansas;   Kentucky;   Louisiana;   Maine;   Maryland;   Massachusetts;   Michigan;   Minnesota;   Mississippi;   Missouri;   Montana;   Nebraska;   Nevada;   New Hampshire;   New Jersey;   New Mexico;   New York City;   New York;   North Carolina;   North Dakota;   Ohio;   Oklahoma;   Oregon;   Pennsylvania;   Rhode Island;   South Carolina;   South Dakota;   Tennessee;   Texas;   Utah;   Vermont;   Virginia;   Washington, DC;   Washington;   West Virginia;   Wisconsin;   Wyoming

USA Territories: American Samoa (USA)   Guam (USA)   Puerto Rico (USA)   Virgin Islands (USA)   Northern Mariana Islands (USA)

USA Compact Free Associations: The Federated States of Micronesia (USA)   Marshall Islands (USA)   Republic of Palau (USA)

Canada: Alberta;   British Columbia;   Manitoba;   New Brunswick;   Newfoundland and Labrador;   Northwest Territories;   Nova Scotia;   Nunavut;   Ontario;   Prince Edward Island;   Quebec;   Saskatchewan;   Yukon;


International country outside of the USA, Israel and Canada.

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